Toxoplasma gondii in beef consumed in France: regional variation in seroprevalence and parasite isolation
In France, the consumption of cattle and sheep meat appears to be a risk factor for infection of pregnant women with Toxoplasma gondii. Several nation-wide surveys in France have investigated the prevalence of T. gondii in sheep and pig meat, but little is known at present about the prevalence of th...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2019-01-01
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| Series: | Parasite |
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| Online Access: | https://www.parasite-journal.org/articles/parasite/full_html/2019/01/parasite180145/parasite180145.html |
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| author | Blaga Radu Aubert Dominique Thébault Anne Perret Catherine Geers Régine Thomas Myriam Alliot Annie Djokic Vitomir Ortis Naïma Halos Lénaïg Durand Benoît Mercier Aurélien Villena Isabelle Boireau Pascal |
| author_facet | Blaga Radu Aubert Dominique Thébault Anne Perret Catherine Geers Régine Thomas Myriam Alliot Annie Djokic Vitomir Ortis Naïma Halos Lénaïg Durand Benoît Mercier Aurélien Villena Isabelle Boireau Pascal |
| author_sort | Blaga Radu |
| collection | DOAJ |
| description | In France, the consumption of cattle and sheep meat appears to be a risk factor for infection of pregnant women with Toxoplasma gondii. Several nation-wide surveys in France have investigated the prevalence of T. gondii in sheep and pig meat, but little is known at present about the prevalence of the parasite in beef. The main objective of the present cross-sectional survey was to estimate the seroprevalence of T. gondii infection in beef consumed in France. A secondary objective was to attempt to isolate T. gondii from cattle tissues and to study the geographical and age variations of this seroprevalence. The overall estimate of seroprevalence of T. gondii in bovine carcasses (n = 2912), for a threshold of 1:6 was 17.38%. A strong age effect was observed (p < 0.0001) with a seroprevalence of 5.34% for calves (<8 months) and 23.12% for adults (>8 months). Seroprevalence estimates given by area of birth and area of slaughtering for adults showed that the areas with the highest seroprevalence were not the same between these two variables. Only two strains, corresponding to genotype II, were isolated from heart samples, indicating that there is a limited risk of human infection with T. gondii, which needs to be correlated with the food habit of consuming raw or undercook (bleu or saignant) beef. However, new questions have emerged, especially concerning the isolation of parasites from beef and the precise role of bovines, generally described as poor hosts for T. gondii, in human infection. |
| first_indexed | 2024-03-11T14:10:25Z |
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| id | doaj.art-a9ef33bc759e4bd3bdd1617ac9b4244c |
| institution | Directory Open Access Journal |
| issn | 1776-1042 |
| language | English |
| last_indexed | 2024-03-11T14:10:25Z |
| publishDate | 2019-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | Parasite |
| spelling | doaj.art-a9ef33bc759e4bd3bdd1617ac9b4244c2023-11-02T00:28:04ZengEDP SciencesParasite1776-10422019-01-01267710.1051/parasite/2019076parasite180145Toxoplasma gondii in beef consumed in France: regional variation in seroprevalence and parasite isolationBlaga RaduAubert Dominique0Thébault Anne1Perret Catherine2Geers Régine3Thomas Myriam4Alliot Annie5Djokic Vitomir6Ortis Naïma7Halos LénaïgDurand Benoît8Mercier AurélienVillena Isabelle9Boireau Pascal10National Reference Center on Toxoplasmosis, Toxoplasma Biological Resources Center, CHU Reims and EA7510, SFR CAP-Santé, University of Reims Champagne-Ardenne, USC EpiToxo ANSESANSES, Direction de l’évaluation des risques, Unité Méthodes et EtudesUMR BIPAR, ANSES, Ecole Nationale Vétérinaire d’Alfort, INRA, Université Paris-Est, National Reference Laboratory for Foodborne Parasites, Animal Health LaboratoryNational Reference Center on Toxoplasmosis, Toxoplasma Biological Resources Center, CHU Reims and EA7510, SFR CAP-Santé, University of Reims Champagne-Ardenne, USC EpiToxo ANSESUMR BIPAR, ANSES, Ecole Nationale Vétérinaire d’Alfort, INRA, Université Paris-Est, National Reference Laboratory for Foodborne Parasites, Animal Health LaboratoryUMR BIPAR, ANSES, Ecole Nationale Vétérinaire d’Alfort, INRA, Université Paris-Est, National Reference Laboratory for Foodborne Parasites, Animal Health LaboratoryUMR BIPAR, ANSES, Ecole Nationale Vétérinaire d’Alfort, INRA, Université Paris-Est, National Reference Laboratory for Foodborne Parasites, Animal Health LaboratoryNational Reference Center on Toxoplasmosis, Toxoplasma Biological Resources Center, CHU Reims and EA7510, SFR CAP-Santé, University of Reims Champagne-Ardenne, USC EpiToxo ANSESEpidemiology Unit, Paris-Est University, Laboratory for Animal Health, French Agency for Food, Environmental and Occupational Health and Safety (ANSES)National Reference Center on Toxoplasmosis, Toxoplasma Biological Resources Center, CHU Reims and EA7510, SFR CAP-Santé, University of Reims Champagne-Ardenne, USC EpiToxo ANSESUMR BIPAR, ANSES, Ecole Nationale Vétérinaire d’Alfort, INRA, Université Paris-Est, National Reference Laboratory for Foodborne Parasites, Animal Health LaboratoryIn France, the consumption of cattle and sheep meat appears to be a risk factor for infection of pregnant women with Toxoplasma gondii. Several nation-wide surveys in France have investigated the prevalence of T. gondii in sheep and pig meat, but little is known at present about the prevalence of the parasite in beef. The main objective of the present cross-sectional survey was to estimate the seroprevalence of T. gondii infection in beef consumed in France. A secondary objective was to attempt to isolate T. gondii from cattle tissues and to study the geographical and age variations of this seroprevalence. The overall estimate of seroprevalence of T. gondii in bovine carcasses (n = 2912), for a threshold of 1:6 was 17.38%. A strong age effect was observed (p < 0.0001) with a seroprevalence of 5.34% for calves (<8 months) and 23.12% for adults (>8 months). Seroprevalence estimates given by area of birth and area of slaughtering for adults showed that the areas with the highest seroprevalence were not the same between these two variables. Only two strains, corresponding to genotype II, were isolated from heart samples, indicating that there is a limited risk of human infection with T. gondii, which needs to be correlated with the food habit of consuming raw or undercook (bleu or saignant) beef. However, new questions have emerged, especially concerning the isolation of parasites from beef and the precise role of bovines, generally described as poor hosts for T. gondii, in human infection.https://www.parasite-journal.org/articles/parasite/full_html/2019/01/parasite180145/parasite180145.htmltoxoplasma gondiibovinesmeatstrain isolationprevalences |
| spellingShingle | Blaga Radu Aubert Dominique Thébault Anne Perret Catherine Geers Régine Thomas Myriam Alliot Annie Djokic Vitomir Ortis Naïma Halos Lénaïg Durand Benoît Mercier Aurélien Villena Isabelle Boireau Pascal Toxoplasma gondii in beef consumed in France: regional variation in seroprevalence and parasite isolation Parasite toxoplasma gondii bovines meat strain isolation prevalences |
| title | Toxoplasma gondii in beef consumed in France: regional variation in seroprevalence and parasite isolation |
| title_full | Toxoplasma gondii in beef consumed in France: regional variation in seroprevalence and parasite isolation |
| title_fullStr | Toxoplasma gondii in beef consumed in France: regional variation in seroprevalence and parasite isolation |
| title_full_unstemmed | Toxoplasma gondii in beef consumed in France: regional variation in seroprevalence and parasite isolation |
| title_short | Toxoplasma gondii in beef consumed in France: regional variation in seroprevalence and parasite isolation |
| title_sort | toxoplasma gondii in beef consumed in france regional variation in seroprevalence and parasite isolation |
| topic | toxoplasma gondii bovines meat strain isolation prevalences |
| url | https://www.parasite-journal.org/articles/parasite/full_html/2019/01/parasite180145/parasite180145.html |
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