A rare presentation of Guillain-Barre syndrome with GQ1b positivity: A case report

Rationale: To report a case of cervicobrachial variant of acute inflammatory demyelinating polyneuropathy presenting with papilledema and GQ1b positivity. Patient concern: A 35-year-old female, 68 days postpartum, presented with headache, vomiting, and gait difficulty in swallowing with bilateral up...

Full description

Bibliographic Details
Main Authors: Minu George, Neena Baby, Pradeep Mathew Koshy, Rajendran Ullatil, Sureshkumar Radhakrishnan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Asian Pacific Journal of Tropical Medicine
Subjects:
Online Access:http://www.apjtm.org/article.asp?issn=1995-7645;year=2022;volume=15;issue=7;spage=332;epage=334;aulast=George
_version_ 1818483351580835840
author Minu George
Neena Baby
Pradeep Mathew Koshy
Rajendran Ullatil
Sureshkumar Radhakrishnan
author_facet Minu George
Neena Baby
Pradeep Mathew Koshy
Rajendran Ullatil
Sureshkumar Radhakrishnan
author_sort Minu George
collection DOAJ
description Rationale: To report a case of cervicobrachial variant of acute inflammatory demyelinating polyneuropathy presenting with papilledema and GQ1b positivity. Patient concern: A 35-year-old female, 68 days postpartum, presented with headache, vomiting, and gait difficulty in swallowing with bilateral upper limb weakness and difficulty in walking, 13 days after ChAdOx1 nCoV-19 vaccination. Diagnosis: Guillain-Barre syndrome with GQ1b positivity. Intervention: Five cycles of plasmapheresis were given. Outcome: The patient’s clinical condition improved. Palatal weakness improved and she could walk without support. There were mild sensory symptoms involving upper limbs which gradually improved. Lessons: AIDP should be considered in case of weakness following ChAdOx1 nCoV-19 vaccination. Albumino-cytological dissociation and anti-GQ1b positivity are needed to confirmed the diagnosis.
first_indexed 2024-12-10T11:59:00Z
format Article
id doaj.art-a9ef3451ba9149ab8757ec1ae3c063db
institution Directory Open Access Journal
issn 2352-4146
language English
last_indexed 2024-12-10T11:59:00Z
publishDate 2022-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Asian Pacific Journal of Tropical Medicine
spelling doaj.art-a9ef3451ba9149ab8757ec1ae3c063db2022-12-22T01:49:41ZengWolters Kluwer Medknow PublicationsAsian Pacific Journal of Tropical Medicine2352-41462022-01-0115733233410.4103/1995-7645.351765A rare presentation of Guillain-Barre syndrome with GQ1b positivity: A case reportMinu GeorgeNeena BabyPradeep Mathew KoshyRajendran UllatilSureshkumar RadhakrishnanRationale: To report a case of cervicobrachial variant of acute inflammatory demyelinating polyneuropathy presenting with papilledema and GQ1b positivity. Patient concern: A 35-year-old female, 68 days postpartum, presented with headache, vomiting, and gait difficulty in swallowing with bilateral upper limb weakness and difficulty in walking, 13 days after ChAdOx1 nCoV-19 vaccination. Diagnosis: Guillain-Barre syndrome with GQ1b positivity. Intervention: Five cycles of plasmapheresis were given. Outcome: The patient’s clinical condition improved. Palatal weakness improved and she could walk without support. There were mild sensory symptoms involving upper limbs which gradually improved. Lessons: AIDP should be considered in case of weakness following ChAdOx1 nCoV-19 vaccination. Albumino-cytological dissociation and anti-GQ1b positivity are needed to confirmed the diagnosis.http://www.apjtm.org/article.asp?issn=1995-7645;year=2022;volume=15;issue=7;spage=332;epage=334;aulast=Georgechadox1ncov-19; papilledema; albuminocytological dissociation; guillain-barre syndrome; acute inflammatory demyelinating polyneuropathy
spellingShingle Minu George
Neena Baby
Pradeep Mathew Koshy
Rajendran Ullatil
Sureshkumar Radhakrishnan
A rare presentation of Guillain-Barre syndrome with GQ1b positivity: A case report
Asian Pacific Journal of Tropical Medicine
chadox1ncov-19; papilledema; albuminocytological dissociation; guillain-barre syndrome; acute inflammatory demyelinating polyneuropathy
title A rare presentation of Guillain-Barre syndrome with GQ1b positivity: A case report
title_full A rare presentation of Guillain-Barre syndrome with GQ1b positivity: A case report
title_fullStr A rare presentation of Guillain-Barre syndrome with GQ1b positivity: A case report
title_full_unstemmed A rare presentation of Guillain-Barre syndrome with GQ1b positivity: A case report
title_short A rare presentation of Guillain-Barre syndrome with GQ1b positivity: A case report
title_sort rare presentation of guillain barre syndrome with gq1b positivity a case report
topic chadox1ncov-19; papilledema; albuminocytological dissociation; guillain-barre syndrome; acute inflammatory demyelinating polyneuropathy
url http://www.apjtm.org/article.asp?issn=1995-7645;year=2022;volume=15;issue=7;spage=332;epage=334;aulast=George
work_keys_str_mv AT minugeorge ararepresentationofguillainbarresyndromewithgq1bpositivityacasereport
AT neenababy ararepresentationofguillainbarresyndromewithgq1bpositivityacasereport
AT pradeepmathewkoshy ararepresentationofguillainbarresyndromewithgq1bpositivityacasereport
AT rajendranullatil ararepresentationofguillainbarresyndromewithgq1bpositivityacasereport
AT sureshkumarradhakrishnan ararepresentationofguillainbarresyndromewithgq1bpositivityacasereport
AT minugeorge rarepresentationofguillainbarresyndromewithgq1bpositivityacasereport
AT neenababy rarepresentationofguillainbarresyndromewithgq1bpositivityacasereport
AT pradeepmathewkoshy rarepresentationofguillainbarresyndromewithgq1bpositivityacasereport
AT rajendranullatil rarepresentationofguillainbarresyndromewithgq1bpositivityacasereport
AT sureshkumarradhakrishnan rarepresentationofguillainbarresyndromewithgq1bpositivityacasereport