An analytic study on the effect of alginate on the velocity profiles of blood in rectangular microchannels using microparticle image velocimetry.

It is desired to understand the effect of alginic acid sodium salt from brown algae (alginate) as a viscosity modifier on the behavior of blood in vitro using a micro-particle image velocimetry (µPIV) system. The effect of alginate on the shape of the velocity profile, the flow rate and the maximum...

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主要な著者: Katie L Pitts, Marianne Fenech
フォーマット: 論文
言語:English
出版事項: Public Library of Science (PLoS) 2013-01-01
シリーズ:PLoS ONE
オンライン・アクセス:http://europepmc.org/articles/PMC3758353?pdf=render
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author Katie L Pitts
Marianne Fenech
author_facet Katie L Pitts
Marianne Fenech
author_sort Katie L Pitts
collection DOAJ
description It is desired to understand the effect of alginic acid sodium salt from brown algae (alginate) as a viscosity modifier on the behavior of blood in vitro using a micro-particle image velocimetry (µPIV) system. The effect of alginate on the shape of the velocity profile, the flow rate and the maximum velocity achieved in rectangular microchannels channels are measured. The channels were constructed of polydimethylsiloxane (PDMS), a biocompatible silicone. Porcine blood cells suspended in saline was used as the working fluid at twenty percent hematocrit (H = 20). While alginate was only found to have minimal effect on the maximum velocity and the flow rate achieved, it was found to significantly affect the shear rate at the wall by between eight to a hundred percent.
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spelling doaj.art-a9f16f1106c7442992c8317e57d6be7d2022-12-21T18:49:01ZengPublic Library of Science (PLoS)PLoS ONE1932-62032013-01-0188e7290910.1371/journal.pone.0072909An analytic study on the effect of alginate on the velocity profiles of blood in rectangular microchannels using microparticle image velocimetry.Katie L PittsMarianne FenechIt is desired to understand the effect of alginic acid sodium salt from brown algae (alginate) as a viscosity modifier on the behavior of blood in vitro using a micro-particle image velocimetry (µPIV) system. The effect of alginate on the shape of the velocity profile, the flow rate and the maximum velocity achieved in rectangular microchannels channels are measured. The channels were constructed of polydimethylsiloxane (PDMS), a biocompatible silicone. Porcine blood cells suspended in saline was used as the working fluid at twenty percent hematocrit (H = 20). While alginate was only found to have minimal effect on the maximum velocity and the flow rate achieved, it was found to significantly affect the shear rate at the wall by between eight to a hundred percent.http://europepmc.org/articles/PMC3758353?pdf=render
spellingShingle Katie L Pitts
Marianne Fenech
An analytic study on the effect of alginate on the velocity profiles of blood in rectangular microchannels using microparticle image velocimetry.
PLoS ONE
title An analytic study on the effect of alginate on the velocity profiles of blood in rectangular microchannels using microparticle image velocimetry.
title_full An analytic study on the effect of alginate on the velocity profiles of blood in rectangular microchannels using microparticle image velocimetry.
title_fullStr An analytic study on the effect of alginate on the velocity profiles of blood in rectangular microchannels using microparticle image velocimetry.
title_full_unstemmed An analytic study on the effect of alginate on the velocity profiles of blood in rectangular microchannels using microparticle image velocimetry.
title_short An analytic study on the effect of alginate on the velocity profiles of blood in rectangular microchannels using microparticle image velocimetry.
title_sort analytic study on the effect of alginate on the velocity profiles of blood in rectangular microchannels using microparticle image velocimetry
url http://europepmc.org/articles/PMC3758353?pdf=render
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