Combination of Clptm1L and TMEM207 Expression as a Robust Prognostic Marker in Oral Squamous Cell Carcinoma

Combination of Clptm1L and TMEM207 Expression as a Robust Prognostic Marker in Oral Squamous Cell Carcinoma

Overexpression of Cleft Lip and Palate Transmembrane 1-Like (Clptm1L) confers cancer cell survival through the endoplasmic reticulum (ER) stress survival signaling pathway, while TMEM207 impairs the tumor suppressor function of WW domain containing oxidoreductase (WWOX), which sensitizes cancer cell...

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Détails bibliographiques
Auteurs principaux: Kimika Hano, Kiichi Hatano, Chiemi Saigo, Yusuke Kito, Toshiyuki Shibata, Tamotsu Takeuchi
Format: Article
Langue:English
Publié: Frontiers Media S.A. 2021-03-01
Collection:Frontiers in Oral Health
Sujets:
OSCC
prognosis
TMEM207
CLPTM1L
ER-stress
WWOX
Accès en ligne:https://www.frontiersin.org/articles/10.3389/froh.2021.638213/full

Internet

https://www.frontiersin.org/articles/10.3389/froh.2021.638213/full

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