Thrombocytopenia: the most frequent haemostatic disorder in the ICU

Thrombocytopenia is the most common haemostatic disorder in patients admitted to Intensive Care Units (ICUs). The mechanisms contributing to a decrease in the platelet count in critically ill patients are multifactorial, among which sepsis and trauma are the most frequent. A differential diagnosis o...

Full description

Bibliographic Details
Main Authors: Jan Pluta, Janusz Trzebicki
Format: Article
Language:English
Published: Termedia Publishing House 2019-09-01
Series:Anaesthesiology Intensive Therapy
Subjects:
Online Access:https://www.termedia.pl/Thrombocytopenia-the-most-frequent-haemostatic-disorder-in-the-ICU,118,37723,1,1.html
Description
Summary:Thrombocytopenia is the most common haemostatic disorder in patients admitted to Intensive Care Units (ICUs). The mechanisms contributing to a decrease in the platelet count in critically ill patients are multifactorial, among which sepsis and trauma are the most frequent. A differential diagnosis of profound thrombocytopenia is crucial for effective treatment. A low platelet count is a strong independent predictor of morbidity and mortality because it is associated with life-threatening bleeding or thrombosis. This article aims to outline the definition and pathophysiology of thrombocytopenia and present a three-step algorithm of the clinical management of this haemostatic disorder.
ISSN:1642-5758
1731-2531