Endothelial Nox5 Expression Modulates Glucose Uptake and Lipid Accumulation in Mice Fed a High-Fat Diet and 3T3-L1 Adipocytes Treated with Glucose and Palmitic Acid

Endothelial Nox5 Expression Modulates Glucose Uptake and Lipid Accumulation in Mice Fed a High-Fat Diet and 3T3-L1 Adipocytes Treated with Glucose and Palmitic Acid

Obesity is a global health issue associated with insulin resistance and altered lipid homeostasis. It has been described that reactive oxygen species (ROS) derived from nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) activity are involved in the development of these pathologies. Th...

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Bibliographic Details
Main Authors: Jorge G. García, Eduardo Ansorena, Fermín I. Milagro, Guillermo Zalba, Carlos de Miguel
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
obesity
NADPH oxidase 5
lipid homeostasis
glucose uptake
Caveolin 1
Glut4
Online Access:https://www.mdpi.com/1422-0067/22/5/2729

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