Ca2+-activated Cl- channels of the ClCa family express in the cilia of a subset of rat olfactory sensory neurons.

Ca2+-activated Cl- channels of the ClCa family express in the cilia of a subset of rat olfactory sensory neurons.

The Ca(2+)-activated Cl(-) channel is considered a key constituent of odor transduction. Odorant binding to a specific receptor in the cilia of olfactory sensory neurons (OSNs) triggers a cAMP cascade that mediates the opening of a cationic cyclic nucleotide-gated channel (CNG), allowing Ca(2+) infl...

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Bibliographic Details
Main Authors: Carolina Gonzalez-Silva, Jorge Vera, María Rosa Bono, Christian González-Billault, Brooke Baxter, Anne Hansen, Robert Lopez, Emily A Gibson, Diego Restrepo, Juan Bacigalupo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3706372?pdf=render

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