Asparaginase activity monitoring in pediatric acute lymphoblastic leukemia: A cross‐sectional nationwide study in Spain

Asparaginase activity monitoring in pediatric acute lymphoblastic leukemia: A cross‐sectional nationwide study in Spain

Abstract Background A cross‐sectional nationwide study was designed to assess national compliance with international consensus/guidelines of monitoring asparaginase levels in children with acute lymphoblastic leukemia (ALL) treated with asparaginase in routine clinical practice. Methods An ad hoc qu...

Full description

Bibliographic Details
Main Authors:	Álvaro Lassaletta, Fernando Gutiérrez, the PEGASO study investigators
Format:	Article
Language:	English
Published:	Wiley 2023-02-01
Series:	Cancer Reports
Subjects:	acute lymphoblastic leukemia asparaginase asparagine cross‐ sectional study survey
Online Access:	https://doi.org/10.1002/cnr2.1729

Similar Items

Toxicity of L-asparaginase drugs in acute lymphoblastic leukemia treatment
by: T. T. Valiev
Published: (2023-09-01)

Clinical summary of pediatric acute lymphoblastic leukemia patients complicated with asparaginase-associated pancreatitis in SCCLG-ALL-2016 protocol
by: Jian Wang, et al.
Published: (2023-12-01)

Rationale for a pediatric-inspired approach in the adolescent and young adult population with acute lymphoblastic leukemia, with a focus on asparaginase treatment
by: Carmelo Rizzari, et al.
Published: (2014-09-01)

Evaluating the Frequencies of CNOT3, GRIA1, NFATC2, and PNPLA3 Variant Alleles and Their Association with L-Asparaginase Hypersensitivity in Pediatric Acute Lymphoblastic Leukemia in Addis Ababa, Ethiopia
by: Ali AM, et al.
Published: (2023-08-01)

Differential impact of asparaginase discontinuation on outcomes of children with T‐cell acute lymphoblastic leukemia and T‐cell lymphoblastic lymphoma
by: Hisashi Ishida, et al.
Published: (2024-06-01)

Peg-asparaginase associated toxicities in children with acute lymphoblastic leukemia: A single-center cross-sectional study
by: Sameh Awwad, et al.
Published: (2024-03-01)

Asparagine: A Metabolite to Be Targeted in Cancers
by: Jie Jiang, et al.
Published: (2021-06-01)

Safety of re‐challenging adults with acute lymphoblastic leukemia with PEG‐asparaginase‐induced severe hypertriglyceridemia when treated with a pediatric‐inspired regimen
by: Ibrahim Al Nabhani, et al.
Published: (2023-02-01)

Optimization of native E. coli-asparaginase therapy in standard risk-group children with acute lymphoblastic leukemia treated by the ALL-MB 2002 protocol
by: M. Yu. Goroshkova, et al.
Published: (2022-11-01)

Expert recommendations for pancreatitis/pancreatic necrosis treatment after L-asparaginase in children with acute lymphoblastic leukemia
by: T. T. Valiev, et al.
Published: (2024-04-01)

Preclinical evaluation of engineered L-asparaginase variants to improve the treatment of Acute Lymphoblastic Leukemia
by: Soumika Sengupta, et al.
Published: (2024-05-01)

Requirement for ER-mitochondria Ca2+ transfer, ROS production and mPTP formation in L-asparaginase-induced apoptosis of acute lymphoblastic leukemia cells
by: Jung Kwon Lee, et al.
Published: (2023-02-01)

Isolation and Purification of L-Asparaginase from Persian Gulf Streptomyces Isolates and Evaluation of It’s Cloned Gene Expression in Escherichia Coli by Real-Time and SDS-PAGE
by: Hadiseh Soofer, et al.
Published: (2020-08-01)

Successful treatment of pancreatitis caused by L-asparaginase in clinical practice
by: Yu. S. Korkina, et al.
Published: (2024-01-01)

Diverse origins of microbial L-asparaginases and their current miscellaneous applications
by: Nada A. Abdelrazek, et al.
Published: (2019-06-01)

Our Experiences with Asparaginase Activity Measurements in Children with Lymphoblastic Diseases
by: Judit Müller, et al.
Published: (2023-07-01)

In-silico evaluation of fungal and bacterial L-asparaginases allergenicity
by: Tekeba Sisay, et al.
Published: (2023-01-01)

Recurrent Cerebral Venous Sinus Thrombosis Occurred in an Acute Lymphoblastic Leukemia Child with Mutated Lipoprotein Lipase Gene during Asparaginase Therapy
by: Shiyuan Wang, et al.
Published: (2024-09-01)

Experience with Generic Pegylated L-asparaginase in Children with Acute Lymphoblastic Leukemia from a Tertiary Care Oncology Center in South India
by: Dhaarani Jayaraman, et al.
Published: (2023-10-01)

Encapsulation of Asparaginase as a Promising Strategy to Improve In Vivo Drug Performance
by: Francisca Villanueva-Flores, et al.
Published: (2021-11-01)

L-asparaginase: New about Well-Known Drug
by: Yuliya S. Korkina, et al.
Published: (2021-07-01)

Insights into Asparaginase Allergic Responses: Exploring Pharmacogenetic Influences
by: Daiane Keller Cecconello, et al.
Published: (2024-08-01)

Monitoring of the treatment with L-asparaginase in children with acute lymphoblastic leukemia – focus on silent inactivation and its influence on the treatment outcome
by: Malgorzata Czogala, et al.
Published: (2023-01-01)

Acute pancreatitis following asparaginase treatment in pediatric acute lymphoblastic leukemia with a heterozygous SPINK1 c.194 + 2T>C intronic variant: a case report
by: Hua Zhou, et al.
Published: (2024-11-01)

Reactions related to asparaginase infusion in a 10-year retrospective cohort
by: Amanda Cabral dos Santos, et al.

Peg-Grafted Liposomes for L-Asparaginase Encapsulation
by: Marina de Souza Guimarães, et al.
Published: (2022-08-01)

Pulmonary embolism in acute lymphoblastic leukemia — An observational study of 1685 patients treated according to the NOPHO ALL2008 protocol
by: Ruta Tuckuviene, et al.
Published: (2020-07-01)

Possible mechanism of metabolic and drug resistance with L-asparaginase therapy in childhood leukaemia
by: Ruizhi Zhou, et al.
Published: (2023-02-01)

L‐asparaginase doses number as a prognostic factor in childhood acute lymphoblastic leukemia: A survival analysis study
by: Amanda Cabral dosSantos, et al.
Published: (2022-08-01)

Follow our path with asparaginase activity: one technique, but different uses in clinical practice
by: Daiane Keller Cecconello, et al.
Published: (2022-11-01)

Pancreatitis in a child with acute lymphoblastic leukemia after Erwinia asparaginase: Evaluation of ultrasonography and computerized tomography as diagnostic tools
by: Fatih Mehmet Azık, et al.
Published: (2010-12-01)

Isolation and Characterization of Glutaminase-free L-asparaginase Produced by Staphylococcus sp. MGM1
by: Gholamhossein Ebrahimipour, et al.
Published: (2020-06-01)

Bacterial Expression of TMTP1-Fused L-Asparaginase for Targeting Leukemia and Metastatic Tumor Cells
by: Mohammad Hassan Kheirandish, et al.
Published: (2023-07-01)

Safety evaluation of the food enzyme asparaginase from the genetically modified Aspergillus oryzae strain NZYM‐SP
by: EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), et al.
Published: (2023-10-01)

Safety evaluation of the food enzyme asparaginase from the genetically modified Bacillus subtilis strain NZYM‐CK
by: EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), et al.
Published: (2023-03-01)

Acquired Clotting Factor Deficits During Treatment with Asparaginase in an Institutional Cohort
by: Papadopoulou V, et al.
Published: (2023-11-01)

Acute pancreatitis following L-asparaginase in acute lymphoblastic leukemia
by: Soulaimane M'harzi, et al.
Published: (2022-01-01)

A Comparative Study on Pseudomonal and Bacillus L. asparaginases
by: Nuzhath Fatima, et al.
Published: (2019-09-01)

Asparaginase-Induced Acute Necrotizing Pancreatitis Resulting in Chronic Pancreatitis and Pseudocyst in an Adult with Acute Lymphocytic Leukemia
by: Randy Adiwinata, et al.
Published: (2023-04-01)

Impact of single-nucleotide variants and individual characteristics on adverse events of L-asparaginase in children with acute lymphoblastic leukemia
by: Jesús Alonso Gándara-Mireles, et al.
Published: (2024-10-01)