A Systematic Review and Meta-Analysis of the Direct Comparison of Second-Generation Cryoballoon Ablation and Contact Force-Sensing Radiofrequency Ablation in Patients with Paroxysmal Atrial Fibrillation
The superiority of second-generation cryoballoon (2G-CB) ablation versus contact force-sensing radiofrequency (CF-RF) ablation in patients with paroxysmal atrial fibrillation (AF) was assessed in this systematic review and meta-analysis. Freedom from atrial tachyarrhythmias (ATAs) (OR = 0.89; 95% co...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Journal of Personalized Medicine |
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| Online Access: | https://www.mdpi.com/2075-4426/12/2/298 |
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| author | Yoga Waranugraha Ardian Rizal Yoga Yuniadi |
| author_facet | Yoga Waranugraha Ardian Rizal Yoga Yuniadi |
| author_sort | Yoga Waranugraha |
| collection | DOAJ |
| description | The superiority of second-generation cryoballoon (2G-CB) ablation versus contact force-sensing radiofrequency (CF-RF) ablation in patients with paroxysmal atrial fibrillation (AF) was assessed in this systematic review and meta-analysis. Freedom from atrial tachyarrhythmias (ATAs) (OR = 0.89; 95% confidence interval [CI] = 0.68 to 1.17; <i>p</i> = 0.41), freedom from AF (OR = 0.93; 95% CI = 0.65 to 1.35; <i>p</i> = 0.72), and acute pulmonary vein isolation (PVI) (OR = 1.17; 95% CI = 0.54 to 2.53; <i>p</i> = 0.70) between 2G-CB ablation and CF-RF ablation were not different. The procedure time for the 2G-CB ablation was shorter (MD = −18.78 min; 95% CI = −27.72 to −9.85 min; <i>p</i> < 0.01), while the fluoroscopy time was similar (MD = 2.66 min; 95% CI = −0.52 to 5.83 min; <i>p</i> = 0.10). In the 2G-CB ablation group, phrenic nerve paralysis was more common (OR = 5.74; 95% CI = 1.80 to 18.31; <i>p</i> = < 0.01). Regarding freedom from ATAs, freedom from AF, and acute PVI, these findings imply that 2G-CB ablation is not superior to CF-RF ablation in paroxysmal AF. Although faster than CF-RF ablation, 2G-CB ablation has a greater risk of phrenic nerve paralysis. |
| first_indexed | 2024-03-09T21:37:34Z |
| format | Article |
| id | doaj.art-aa026cda1c444f65a917847a26ea2e47 |
| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-09T21:37:34Z |
| publishDate | 2022-02-01 |
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| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-aa026cda1c444f65a917847a26ea2e472023-11-23T20:41:14ZengMDPI AGJournal of Personalized Medicine2075-44262022-02-0112229810.3390/jpm12020298A Systematic Review and Meta-Analysis of the Direct Comparison of Second-Generation Cryoballoon Ablation and Contact Force-Sensing Radiofrequency Ablation in Patients with Paroxysmal Atrial FibrillationYoga Waranugraha0Ardian Rizal1Yoga Yuniadi2Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Brawijaya, Universitas Brawijaya Hospital, Malang 65142, IndonesiaDepartment of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Brawijaya, Dr. Saiful Anwar General Hospital, Malang 65111, IndonesiaDepartment of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta Barat 11420, IndonesiaThe superiority of second-generation cryoballoon (2G-CB) ablation versus contact force-sensing radiofrequency (CF-RF) ablation in patients with paroxysmal atrial fibrillation (AF) was assessed in this systematic review and meta-analysis. Freedom from atrial tachyarrhythmias (ATAs) (OR = 0.89; 95% confidence interval [CI] = 0.68 to 1.17; <i>p</i> = 0.41), freedom from AF (OR = 0.93; 95% CI = 0.65 to 1.35; <i>p</i> = 0.72), and acute pulmonary vein isolation (PVI) (OR = 1.17; 95% CI = 0.54 to 2.53; <i>p</i> = 0.70) between 2G-CB ablation and CF-RF ablation were not different. The procedure time for the 2G-CB ablation was shorter (MD = −18.78 min; 95% CI = −27.72 to −9.85 min; <i>p</i> < 0.01), while the fluoroscopy time was similar (MD = 2.66 min; 95% CI = −0.52 to 5.83 min; <i>p</i> = 0.10). In the 2G-CB ablation group, phrenic nerve paralysis was more common (OR = 5.74; 95% CI = 1.80 to 18.31; <i>p</i> = < 0.01). Regarding freedom from ATAs, freedom from AF, and acute PVI, these findings imply that 2G-CB ablation is not superior to CF-RF ablation in paroxysmal AF. Although faster than CF-RF ablation, 2G-CB ablation has a greater risk of phrenic nerve paralysis.https://www.mdpi.com/2075-4426/12/2/298paroxysmal atrial fibrillationcatheter ablationsecond-generation cryoballoon ablationcontact force-sensing radiofrequency ablation |
| spellingShingle | Yoga Waranugraha Ardian Rizal Yoga Yuniadi A Systematic Review and Meta-Analysis of the Direct Comparison of Second-Generation Cryoballoon Ablation and Contact Force-Sensing Radiofrequency Ablation in Patients with Paroxysmal Atrial Fibrillation Journal of Personalized Medicine paroxysmal atrial fibrillation catheter ablation second-generation cryoballoon ablation contact force-sensing radiofrequency ablation |
| title | A Systematic Review and Meta-Analysis of the Direct Comparison of Second-Generation Cryoballoon Ablation and Contact Force-Sensing Radiofrequency Ablation in Patients with Paroxysmal Atrial Fibrillation |
| title_full | A Systematic Review and Meta-Analysis of the Direct Comparison of Second-Generation Cryoballoon Ablation and Contact Force-Sensing Radiofrequency Ablation in Patients with Paroxysmal Atrial Fibrillation |
| title_fullStr | A Systematic Review and Meta-Analysis of the Direct Comparison of Second-Generation Cryoballoon Ablation and Contact Force-Sensing Radiofrequency Ablation in Patients with Paroxysmal Atrial Fibrillation |
| title_full_unstemmed | A Systematic Review and Meta-Analysis of the Direct Comparison of Second-Generation Cryoballoon Ablation and Contact Force-Sensing Radiofrequency Ablation in Patients with Paroxysmal Atrial Fibrillation |
| title_short | A Systematic Review and Meta-Analysis of the Direct Comparison of Second-Generation Cryoballoon Ablation and Contact Force-Sensing Radiofrequency Ablation in Patients with Paroxysmal Atrial Fibrillation |
| title_sort | systematic review and meta analysis of the direct comparison of second generation cryoballoon ablation and contact force sensing radiofrequency ablation in patients with paroxysmal atrial fibrillation |
| topic | paroxysmal atrial fibrillation catheter ablation second-generation cryoballoon ablation contact force-sensing radiofrequency ablation |
| url | https://www.mdpi.com/2075-4426/12/2/298 |
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