Genome variants associated with RNA splicing variations in bovine are extensively shared between tissues

Genome variants associated with RNA splicing variations in bovine are extensively shared between tissues

Abstract Background Mammalian phenotypes are shaped by numerous genome variants, many of which may regulate gene transcription or RNA splicing. To identify variants with regulatory functions in cattle, an important economic and model species, we used sequence variants to map a type of expression qua...

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Bibliographic Details
Main Authors: Ruidong Xiang, Ben J. Hayes, Christy J. Vander Jagt, Iona M. MacLeod, Majid Khansefid, Phil J. Bowman, Zehu Yuan, Claire P. Prowse-Wilkins, Coralie M. Reich, Brett A. Mason, Josie B. Garner, Leah C. Marett, Yizhou Chen, Sunduimijid Bolormaa, Hans D. Daetwyler, Amanda J. Chamberlain, Michael E. Goddard
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Genomics
Subjects:
RNA splicing
Gene expression
Expression QTL
sQTL
Genetic correlations
Local genomic relationship matrices (LGRM)
Online Access:http://link.springer.com/article/10.1186/s12864-018-4902-8

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