Actin capping protein regulates postsynaptic spine development through CPI-motif interactions

Dendritic spines are small actin-rich protrusions essential for the formation of functional circuits in the mammalian brain. During development, spines begin as dynamic filopodia-like protrusions that are then replaced by relatively stable spines containing an expanded head. Remodeling of the actin...

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Bibliographic Details
Main Authors: Kenneth R. Myers, Yanjie Fan, Patrick McConnell, John A. Cooper, James Q. Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.1020949/full