Radiological Findings of Thoracic Sarcoidosis in an Indian Cohort: A Retrospective Study
Introduction: Sarcoidosis is commonly mistaken for tuberculosis in India. Imaging is of paramount importance in making a correct diagnosis, but, most of the published literature available on radiological findings of sarcoidosis is from the Western population. Aim: To study the radiological find...
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JCDR Research and Publications Pvt. Ltd.
2021-10-01
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| Series: | International Journal of Anatomy Radiology and Surgery |
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| Online Access: | http://www.ijars.net/articles/PDF/2716/48210_CE[Ra1]_F(SHU)_PF1(SY_SHU)_PFA(AB_KM)_PN(KM).pdf |
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| author | Tharani Putta Aparna Irodi RV Leena Binita Riya Chacko Devasahayam Christopher |
| author_facet | Tharani Putta Aparna Irodi RV Leena Binita Riya Chacko Devasahayam Christopher |
| author_sort | Tharani Putta |
| collection | DOAJ |
| description | Introduction: Sarcoidosis is commonly mistaken for tuberculosis
in India. Imaging is of paramount importance in making a
correct diagnosis, but, most of the published literature available
on radiological findings of sarcoidosis is from the Western
population.
Aim: To study the radiological findings of thoracic sarcoidosis
in Indian patients.
Materials and Methods: This was a retrospective descriptive
study done in a tertiary hospital in Southern India after
obtaining clearance from Institutional Review board and Ethics
Committee (IRB Min no 6997). Ninety-six patients diagnosed
with sarcoidosis between January 2001 and August 2009 based
on a combination of clinical, radiological and histopathological
findings were included in the study. Their chest radiographs
and High-Resolution Computerised Tomography (HRCT) thorax
at presentation were reviewed and radiological findings were
documented on a proforma. Statistical Package for the Social
Sciences (SPSS, IBM Corp., Armonk, NY) software version 21.0
was used for statistical analysis.
Results: The HRCT was abnormal in all the study patients
with lymphadenopathy seen in 87 patients (90.6%) and lung
parenchymal abnormality in 92 patients (95.8%). Mediastinal
nodes were more commonly seen when compared with hilar
lymphadenopathy. The typical lung parenchymal findings seen
were juxta-fissural or subpleural nodules and peribronchovascular
nodular interstitial thickening. Late irreversible findings were seen
at least focally in 43 patients (45%). The classically described
upper zone lung predilection was not seen in this study.
Conclusion: Paratracheal and subcarinal lymphadenopathy
are more common than hilar lymphadenopathy in sarcoidosis.
Despite overlapping radiological findings between pulmonary
sarcoidosis and tuberculosis, the presence of hyperdense
nodes, fissural nodularity, peribronchovascular nodular interstitial
thickening with perihilar prominence of findings should favour
diagnosis of sarcoidosis. |
| first_indexed | 2024-12-20T12:54:05Z |
| format | Article |
| id | doaj.art-aa0c6a3c62514792a322696afc8b1ca4 |
| institution | Directory Open Access Journal |
| issn | 2277-8543 2455-6874 |
| language | English |
| last_indexed | 2024-12-20T12:54:05Z |
| publishDate | 2021-10-01 |
| publisher | JCDR Research and Publications Pvt. Ltd. |
| record_format | Article |
| series | International Journal of Anatomy Radiology and Surgery |
| spelling | doaj.art-aa0c6a3c62514792a322696afc8b1ca42022-12-21T19:40:07ZengJCDR Research and Publications Pvt. Ltd.International Journal of Anatomy Radiology and Surgery2277-85432455-68742021-10-011004252910.7860/IJARS/2021/48210:2716Radiological Findings of Thoracic Sarcoidosis in an Indian Cohort: A Retrospective StudyTharani Putta0Aparna Irodi1RV Leena2Binita Riya Chacko3Devasahayam Christopher4Associate Professor, Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India. Professor, Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India.Professor, Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India.Professor, Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India.Professor, Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India.Introduction: Sarcoidosis is commonly mistaken for tuberculosis in India. Imaging is of paramount importance in making a correct diagnosis, but, most of the published literature available on radiological findings of sarcoidosis is from the Western population. Aim: To study the radiological findings of thoracic sarcoidosis in Indian patients. Materials and Methods: This was a retrospective descriptive study done in a tertiary hospital in Southern India after obtaining clearance from Institutional Review board and Ethics Committee (IRB Min no 6997). Ninety-six patients diagnosed with sarcoidosis between January 2001 and August 2009 based on a combination of clinical, radiological and histopathological findings were included in the study. Their chest radiographs and High-Resolution Computerised Tomography (HRCT) thorax at presentation were reviewed and radiological findings were documented on a proforma. Statistical Package for the Social Sciences (SPSS, IBM Corp., Armonk, NY) software version 21.0 was used for statistical analysis. Results: The HRCT was abnormal in all the study patients with lymphadenopathy seen in 87 patients (90.6%) and lung parenchymal abnormality in 92 patients (95.8%). Mediastinal nodes were more commonly seen when compared with hilar lymphadenopathy. The typical lung parenchymal findings seen were juxta-fissural or subpleural nodules and peribronchovascular nodular interstitial thickening. Late irreversible findings were seen at least focally in 43 patients (45%). The classically described upper zone lung predilection was not seen in this study. Conclusion: Paratracheal and subcarinal lymphadenopathy are more common than hilar lymphadenopathy in sarcoidosis. Despite overlapping radiological findings between pulmonary sarcoidosis and tuberculosis, the presence of hyperdense nodes, fissural nodularity, peribronchovascular nodular interstitial thickening with perihilar prominence of findings should favour diagnosis of sarcoidosis.http://www.ijars.net/articles/PDF/2716/48210_CE[Ra1]_F(SHU)_PF1(SY_SHU)_PFA(AB_KM)_PN(KM).pdfhigh resolution computed tomographyhyperdense nodesinterstitial thickeningperilymphatic nodules |
| spellingShingle | Tharani Putta Aparna Irodi RV Leena Binita Riya Chacko Devasahayam Christopher Radiological Findings of Thoracic Sarcoidosis in an Indian Cohort: A Retrospective Study International Journal of Anatomy Radiology and Surgery high resolution computed tomography hyperdense nodes interstitial thickening perilymphatic nodules |
| title | Radiological Findings of Thoracic Sarcoidosis in an Indian Cohort: A Retrospective Study |
| title_full | Radiological Findings of Thoracic Sarcoidosis in an Indian Cohort: A Retrospective Study |
| title_fullStr | Radiological Findings of Thoracic Sarcoidosis in an Indian Cohort: A Retrospective Study |
| title_full_unstemmed | Radiological Findings of Thoracic Sarcoidosis in an Indian Cohort: A Retrospective Study |
| title_short | Radiological Findings of Thoracic Sarcoidosis in an Indian Cohort: A Retrospective Study |
| title_sort | radiological findings of thoracic sarcoidosis in an indian cohort a retrospective study |
| topic | high resolution computed tomography hyperdense nodes interstitial thickening perilymphatic nodules |
| url | http://www.ijars.net/articles/PDF/2716/48210_CE[Ra1]_F(SHU)_PF1(SY_SHU)_PFA(AB_KM)_PN(KM).pdf |
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