Comparison of the effectiveness of lauromacrogol injection for ablation and microwave ablation in the treatment of predominantly cystic thyroid nodules: a multicentre study
Abstract Purpose To compare the therapeutic efficacy and safety of microwave ablation (MWA) and lauromacrogol injection for ablation (LIA) for benign predominantly cystic thyroid nodules. Materials and methods In this retrospective study, 85 patients with predominantly cystic thyroid nodules (PCTNs)...
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| Format: | Article |
| Language: | English |
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BMC
2023-08-01
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| Series: | BMC Cancer |
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| Online Access: | https://doi.org/10.1186/s12885-023-11301-7 |
| _version_ | 1797452328791441408 |
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| author | Xin Min Zheng Zhang Yanwei Chen Shuangshuang Zhao Jingwen Ge Huajiao Zhao Yun Cai Hui Chen Jun Shao Yanfei Jing Baoding Chen |
| author_facet | Xin Min Zheng Zhang Yanwei Chen Shuangshuang Zhao Jingwen Ge Huajiao Zhao Yun Cai Hui Chen Jun Shao Yanfei Jing Baoding Chen |
| author_sort | Xin Min |
| collection | DOAJ |
| description | Abstract Purpose To compare the therapeutic efficacy and safety of microwave ablation (MWA) and lauromacrogol injection for ablation (LIA) for benign predominantly cystic thyroid nodules. Materials and methods In this retrospective study, 85 patients with predominantly cystic thyroid nodules (PCTNs) who underwent microwave ablation (MWA) or lauromacrogol injection for ablation (LIA) between June 2019 and August 2022 at three hospitals were included in our research. Forty-six patients were treated with microwave ablation, and thirty-nine patients were treated with lauromacrogol injection for ablation. The baseline characteristics, nodal volume, volume reduction rate (VRR), and incidence of postoperative complications were compared between these two groups. Results After treatment, there were significant differences in the thyroid nodule volume and the volume reduction rate (VRR) at different follow-up times between the groups (p < 0.001). There were no significant differences in the nodal volume or the volume reduction rate (VRR) between the MWA group and the LIA group at 1, 3, 6, and 12 months (p > 0.05). Of note, no serious intraoperative or postoperative complications occurred in the corresponding group. Conclusion MWA and LIA are very effective and safe strategies for the treatment of predominantly cystic thyroid nodules. However, LIA is more advantageous in that it is less expensive and has a shorter length of hospital stay than MWA. |
| first_indexed | 2024-03-09T15:06:57Z |
| format | Article |
| id | doaj.art-aa10f963b9f740e2a0ad6758e2c2997e |
| institution | Directory Open Access Journal |
| issn | 1471-2407 |
| language | English |
| last_indexed | 2024-03-09T15:06:57Z |
| publishDate | 2023-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj.art-aa10f963b9f740e2a0ad6758e2c2997e2023-11-26T13:36:08ZengBMCBMC Cancer1471-24072023-08-012311810.1186/s12885-023-11301-7Comparison of the effectiveness of lauromacrogol injection for ablation and microwave ablation in the treatment of predominantly cystic thyroid nodules: a multicentre studyXin Min0Zheng Zhang1Yanwei Chen2Shuangshuang Zhao3Jingwen Ge4Huajiao Zhao5Yun Cai6Hui Chen7Jun Shao8Yanfei Jing9Baoding Chen10Department of Medical Ultrasound, Affiliated Hospital of Jiangsu UniversityDepartment of Medical Ultrasound, Affiliated Hospital of Jiangsu UniversityDepartment of Medical Ultrasound, Affiliated Hospital of Jiangsu UniversityDepartment of Medical Ultrasound, Affiliated Hospital of Jiangsu UniversityDepartment of Medical Ultrasound, Affiliated Hospital of Jiangsu UniversityDepartment of Medical Ultrasound, Affiliated Hospital of Jiangsu UniversityDepartment of Medical Ultrasound, Affiliated Hospital of Jiangsu UniversityDepartment of Medical Ultrasound, Changzhou First People’s Hospital and The Third Affiliated Hospital of Soochow UniversityDepartment of Medical Ultrasound, The First People’s Hospital of Kunshan Affiliated to Jiangsu UniversityDepartment of Medical Ultrasound, The Fifth People’s Hospital of Wuxi, The Medical School of Jiangnan UniversityDepartment of Medical Ultrasound, Affiliated Hospital of Jiangsu UniversityAbstract Purpose To compare the therapeutic efficacy and safety of microwave ablation (MWA) and lauromacrogol injection for ablation (LIA) for benign predominantly cystic thyroid nodules. Materials and methods In this retrospective study, 85 patients with predominantly cystic thyroid nodules (PCTNs) who underwent microwave ablation (MWA) or lauromacrogol injection for ablation (LIA) between June 2019 and August 2022 at three hospitals were included in our research. Forty-six patients were treated with microwave ablation, and thirty-nine patients were treated with lauromacrogol injection for ablation. The baseline characteristics, nodal volume, volume reduction rate (VRR), and incidence of postoperative complications were compared between these two groups. Results After treatment, there were significant differences in the thyroid nodule volume and the volume reduction rate (VRR) at different follow-up times between the groups (p < 0.001). There were no significant differences in the nodal volume or the volume reduction rate (VRR) between the MWA group and the LIA group at 1, 3, 6, and 12 months (p > 0.05). Of note, no serious intraoperative or postoperative complications occurred in the corresponding group. Conclusion MWA and LIA are very effective and safe strategies for the treatment of predominantly cystic thyroid nodules. However, LIA is more advantageous in that it is less expensive and has a shorter length of hospital stay than MWA.https://doi.org/10.1186/s12885-023-11301-7Microwave ablationLauromacrogol injection for ablationUltrasound medicinePredominantly cystic thyroid nodules |
| spellingShingle | Xin Min Zheng Zhang Yanwei Chen Shuangshuang Zhao Jingwen Ge Huajiao Zhao Yun Cai Hui Chen Jun Shao Yanfei Jing Baoding Chen Comparison of the effectiveness of lauromacrogol injection for ablation and microwave ablation in the treatment of predominantly cystic thyroid nodules: a multicentre study BMC Cancer Microwave ablation Lauromacrogol injection for ablation Ultrasound medicine Predominantly cystic thyroid nodules |
| title | Comparison of the effectiveness of lauromacrogol injection for ablation and microwave ablation in the treatment of predominantly cystic thyroid nodules: a multicentre study |
| title_full | Comparison of the effectiveness of lauromacrogol injection for ablation and microwave ablation in the treatment of predominantly cystic thyroid nodules: a multicentre study |
| title_fullStr | Comparison of the effectiveness of lauromacrogol injection for ablation and microwave ablation in the treatment of predominantly cystic thyroid nodules: a multicentre study |
| title_full_unstemmed | Comparison of the effectiveness of lauromacrogol injection for ablation and microwave ablation in the treatment of predominantly cystic thyroid nodules: a multicentre study |
| title_short | Comparison of the effectiveness of lauromacrogol injection for ablation and microwave ablation in the treatment of predominantly cystic thyroid nodules: a multicentre study |
| title_sort | comparison of the effectiveness of lauromacrogol injection for ablation and microwave ablation in the treatment of predominantly cystic thyroid nodules a multicentre study |
| topic | Microwave ablation Lauromacrogol injection for ablation Ultrasound medicine Predominantly cystic thyroid nodules |
| url | https://doi.org/10.1186/s12885-023-11301-7 |
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