Fructose-bisphosphatase1 (FBP1) alleviates experimental osteoarthritis by regulating Protein crumbs homolog 3 (CRB3)

Fructose-bisphosphatase1 (FBP1) alleviates experimental osteoarthritis by regulating Protein crumbs homolog 3 (CRB3)

Abstract Purpose To identify the role of gluconeogenesis in chondrocytes in osteoarthritis (OA). Materials and methods Cartilage samples were collected from OA patients and C57 mice and were stained with Safranin O-Fast Green to determine the severity of OA. Periodic acid Schiff staining was used to...

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Bibliographic Details
Main Authors: Zhuolun Wang, Xinjie Wang, Liangliang Liu, Xiongtian Guo, Haiyan Zhang, Jianbing Yin, Rengui Lin, Yan Shao, Daozhang Cai
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Arthritis Research & Therapy
Subjects:
Osteoarthritis
Cartilage
Gluconeogenesis
Chondrocyte
Senescence
Online Access:https://doi.org/10.1186/s13075-023-03221-5

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