Anterior lumbar spinal fusion surgery associated with lower risk of stroke, pneumonia, and infection compared to posterior lumbar spinal fusion surgery

Background: Prior studies, comparing anterior and posterior approaches to lumbar fusion surgery, found similar fusion rates and clinical outcomes, but are limited by sample size. Further evaluation of the postoperative complications of each approach is necessary. Methods: The MSpine database by Pear...

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Main Authors: Leland C. McCluskey, Ivan Angelov, Victor J. Wu, Sanchita Gupta, Comron Saifi, Mathew Cyriac
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:North American Spine Society Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666548422000853
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author Leland C. McCluskey
Ivan Angelov
Victor J. Wu
Sanchita Gupta
Comron Saifi
Mathew Cyriac
author_facet Leland C. McCluskey
Ivan Angelov
Victor J. Wu
Sanchita Gupta
Comron Saifi
Mathew Cyriac
author_sort Leland C. McCluskey
collection DOAJ
description Background: Prior studies, comparing anterior and posterior approaches to lumbar fusion surgery, found similar fusion rates and clinical outcomes, but are limited by sample size. Further evaluation of the postoperative complications of each approach is necessary. Methods: The MSpine database by PearlDiver was queried using ICD-9, ICD-10, and CPT codes to identify patients who had undergone single-level anterior or posterior lumbar interbody fusion surgery. Readmission rates, ileus, lower extremity DVT, infection, pneumonia, and stroke were used to compare post-operative complications of an anterior vs. posterior approach. Results: 112,023 patients were included in this study, with 38,529 (34.4%) in the anterior group (ALIF/LLIF) and 73,494 (65.6%) in the posterior group (PLIF/TLIF). At both 30 and 90-days postoperative, patients undergoing an anterior approach to lumbar interbody fusion had a higher odds ratio of lower extremity DVT (30-day OR: 1.19, 90-day OR: 1.16; P<0.05) and ileus complication (30-day OR: 1.87, P= <.05; 90-day OR: 1.81, P<.05). At both 30 and 90-days postoperative, patients undergoing a posterior approach had a higher odds ratio of stroke (30-day: OR: 0.79, 90-day OR: 0.87; P<0.05), transfusion (30-day OR: 0.66, 90-day OR: 0.69; P<.05), infection (30-day OR: 0.88, 90-day OR: 0.91; P <.05), and pneumonia (30-day OR: 0.85, 90-day OR: 0.90; P<.05). There was no statistically significant difference in myocardial infarction or pulmonary embolism between both approaches at 30 and 90-days postoperative. Conclusions: Anterior and posterior approaches for lumbar interbody fusion were associated with differences in postoperative complications at 30 and 90-days. The complication profiles associated with each approach can inform surgeon treatment decisions based on patient profiles.
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spelling doaj.art-aa1a63551d5c41fb9d2ce47fe95af89e2022-12-22T04:23:30ZengElsevierNorth American Spine Society Journal2666-54842022-12-0112100182Anterior lumbar spinal fusion surgery associated with lower risk of stroke, pneumonia, and infection compared to posterior lumbar spinal fusion surgeryLeland C. McCluskey0Ivan Angelov1Victor J. Wu2Sanchita Gupta3Comron Saifi4Mathew Cyriac5Department of Orthopaedic Surgery, Tulane University School of MedicineDepartment of Orthopedics and Sports Medicine, Houston Methodist HospitalDepartment of Orthopaedic Surgery, University of Texas Health Sciences Center - HoustonDepartment of Orthopaedic Surgery, Tulane University School of MedicineDepartment of Orthopedics and Sports Medicine, Houston Methodist Hospital; Corresponding author.Department of Orthopaedic Surgery, Tulane University School of MedicineBackground: Prior studies, comparing anterior and posterior approaches to lumbar fusion surgery, found similar fusion rates and clinical outcomes, but are limited by sample size. Further evaluation of the postoperative complications of each approach is necessary. Methods: The MSpine database by PearlDiver was queried using ICD-9, ICD-10, and CPT codes to identify patients who had undergone single-level anterior or posterior lumbar interbody fusion surgery. Readmission rates, ileus, lower extremity DVT, infection, pneumonia, and stroke were used to compare post-operative complications of an anterior vs. posterior approach. Results: 112,023 patients were included in this study, with 38,529 (34.4%) in the anterior group (ALIF/LLIF) and 73,494 (65.6%) in the posterior group (PLIF/TLIF). At both 30 and 90-days postoperative, patients undergoing an anterior approach to lumbar interbody fusion had a higher odds ratio of lower extremity DVT (30-day OR: 1.19, 90-day OR: 1.16; P<0.05) and ileus complication (30-day OR: 1.87, P= <.05; 90-day OR: 1.81, P<.05). At both 30 and 90-days postoperative, patients undergoing a posterior approach had a higher odds ratio of stroke (30-day: OR: 0.79, 90-day OR: 0.87; P<0.05), transfusion (30-day OR: 0.66, 90-day OR: 0.69; P<.05), infection (30-day OR: 0.88, 90-day OR: 0.91; P <.05), and pneumonia (30-day OR: 0.85, 90-day OR: 0.90; P<.05). There was no statistically significant difference in myocardial infarction or pulmonary embolism between both approaches at 30 and 90-days postoperative. Conclusions: Anterior and posterior approaches for lumbar interbody fusion were associated with differences in postoperative complications at 30 and 90-days. The complication profiles associated with each approach can inform surgeon treatment decisions based on patient profiles.http://www.sciencedirect.com/science/article/pii/S2666548422000853Anterior lumbar interbody fusionPosterior lumbar interbody fusionTransfusionPostoperative complicationsStrokeInfection
spellingShingle Leland C. McCluskey
Ivan Angelov
Victor J. Wu
Sanchita Gupta
Comron Saifi
Mathew Cyriac
Anterior lumbar spinal fusion surgery associated with lower risk of stroke, pneumonia, and infection compared to posterior lumbar spinal fusion surgery
North American Spine Society Journal
Anterior lumbar interbody fusion
Posterior lumbar interbody fusion
Transfusion
Postoperative complications
Stroke
Infection
title Anterior lumbar spinal fusion surgery associated with lower risk of stroke, pneumonia, and infection compared to posterior lumbar spinal fusion surgery
title_full Anterior lumbar spinal fusion surgery associated with lower risk of stroke, pneumonia, and infection compared to posterior lumbar spinal fusion surgery
title_fullStr Anterior lumbar spinal fusion surgery associated with lower risk of stroke, pneumonia, and infection compared to posterior lumbar spinal fusion surgery
title_full_unstemmed Anterior lumbar spinal fusion surgery associated with lower risk of stroke, pneumonia, and infection compared to posterior lumbar spinal fusion surgery
title_short Anterior lumbar spinal fusion surgery associated with lower risk of stroke, pneumonia, and infection compared to posterior lumbar spinal fusion surgery
title_sort anterior lumbar spinal fusion surgery associated with lower risk of stroke pneumonia and infection compared to posterior lumbar spinal fusion surgery
topic Anterior lumbar interbody fusion
Posterior lumbar interbody fusion
Transfusion
Postoperative complications
Stroke
Infection
url http://www.sciencedirect.com/science/article/pii/S2666548422000853
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