Altered patterns of directed connectivity within the reading network of dyslexic children and their relation to reading dysfluency
Reading is a complex cognitive skill subserved by a distributed network of visual and language-related regions. Disruptions of connectivity within this network have been associated with developmental dyslexia but their relation to individual differences in the severity of reading problems remains un...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017-02-01
|
| Series: | Developmental Cognitive Neuroscience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S187892931630055X |
| _version_ | 1828802988670451712 |
|---|---|
| author | Gojko Žarić João M. Correia Gorka Fraga González Jurgen Tijms Maurtis W. van der Molen Leo Blomert Milene Bonte |
| author_facet | Gojko Žarić João M. Correia Gorka Fraga González Jurgen Tijms Maurtis W. van der Molen Leo Blomert Milene Bonte |
| author_sort | Gojko Žarić |
| collection | DOAJ |
| description | Reading is a complex cognitive skill subserved by a distributed network of visual and language-related regions. Disruptions of connectivity within this network have been associated with developmental dyslexia but their relation to individual differences in the severity of reading problems remains unclear. Here we investigate whether dysfunctional connectivity scales with the level of reading dysfluency by examining EEG recordings during visual word and false font processing in 9-year-old typically reading children (TR) and two groups of dyslexic children: severely dysfluent (SDD) and moderately dysfluent (MDD) dyslexics. Results indicated weaker occipital to inferior-temporal connectivity for words in both dyslexic groups relative to TRs. Furthermore, SDDs exhibited stronger connectivity from left central to right inferior-temporal and occipital sites for words relative to TRs, and for false fonts relative to both MDDs and TRs. Importantly, reading fluency was positively related with forward and negatively with backward connectivity. Our results suggest disrupted visual processing of words in both dyslexic groups, together with a compensatory recruitment of right posterior brain regions especially in the SDDs during word and false font processing. Functional connectivity in the brain’s reading network may thus depend on the level of reading dysfluency beyond group differences between dyslexic and typical readers. |
| first_indexed | 2024-12-12T07:13:58Z |
| format | Article |
| id | doaj.art-aa1bc1463ae94e6ca77be54615f30d8b |
| institution | Directory Open Access Journal |
| issn | 1878-9293 1878-9307 |
| language | English |
| last_indexed | 2024-12-12T07:13:58Z |
| publishDate | 2017-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Developmental Cognitive Neuroscience |
| spelling | doaj.art-aa1bc1463ae94e6ca77be54615f30d8b2022-12-22T00:33:33ZengElsevierDevelopmental Cognitive Neuroscience1878-92931878-93072017-02-0123C11310.1016/j.dcn.2016.11.003Altered patterns of directed connectivity within the reading network of dyslexic children and their relation to reading dysfluencyGojko Žarić0João M. Correia1Gorka Fraga González2Jurgen Tijms3Maurtis W. van der Molen4Leo Blomert5Milene Bonte6Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Oxfordlaan 55, 6229EV Maastricht, NetherlandsDepartment of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Oxfordlaan 55, 6229EV Maastricht, NetherlandsDepartment of Developmental Psychology, University of Amsterdam, Nieuwe Achtergracht 129, 1018 WS Amsterdam, NetherlandsDepartment of Developmental Psychology, University of Amsterdam, Nieuwe Achtergracht 129, 1018 WS Amsterdam, NetherlandsDepartment of Developmental Psychology, University of Amsterdam, Nieuwe Achtergracht 129, 1018 WS Amsterdam, NetherlandsDepartment of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Oxfordlaan 55, 6229EV Maastricht, NetherlandsDepartment of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Oxfordlaan 55, 6229EV Maastricht, NetherlandsReading is a complex cognitive skill subserved by a distributed network of visual and language-related regions. Disruptions of connectivity within this network have been associated with developmental dyslexia but their relation to individual differences in the severity of reading problems remains unclear. Here we investigate whether dysfunctional connectivity scales with the level of reading dysfluency by examining EEG recordings during visual word and false font processing in 9-year-old typically reading children (TR) and two groups of dyslexic children: severely dysfluent (SDD) and moderately dysfluent (MDD) dyslexics. Results indicated weaker occipital to inferior-temporal connectivity for words in both dyslexic groups relative to TRs. Furthermore, SDDs exhibited stronger connectivity from left central to right inferior-temporal and occipital sites for words relative to TRs, and for false fonts relative to both MDDs and TRs. Importantly, reading fluency was positively related with forward and negatively with backward connectivity. Our results suggest disrupted visual processing of words in both dyslexic groups, together with a compensatory recruitment of right posterior brain regions especially in the SDDs during word and false font processing. Functional connectivity in the brain’s reading network may thus depend on the level of reading dysfluency beyond group differences between dyslexic and typical readers.http://www.sciencedirect.com/science/article/pii/S187892931630055XDevelopmental dyslexiaReading fluencyVisual word recognitionDirected functional connectivityDirected transfer function |
| spellingShingle | Gojko Žarić João M. Correia Gorka Fraga González Jurgen Tijms Maurtis W. van der Molen Leo Blomert Milene Bonte Altered patterns of directed connectivity within the reading network of dyslexic children and their relation to reading dysfluency Developmental Cognitive Neuroscience Developmental dyslexia Reading fluency Visual word recognition Directed functional connectivity Directed transfer function |
| title | Altered patterns of directed connectivity within the reading network of dyslexic children and their relation to reading dysfluency |
| title_full | Altered patterns of directed connectivity within the reading network of dyslexic children and their relation to reading dysfluency |
| title_fullStr | Altered patterns of directed connectivity within the reading network of dyslexic children and their relation to reading dysfluency |
| title_full_unstemmed | Altered patterns of directed connectivity within the reading network of dyslexic children and their relation to reading dysfluency |
| title_short | Altered patterns of directed connectivity within the reading network of dyslexic children and their relation to reading dysfluency |
| title_sort | altered patterns of directed connectivity within the reading network of dyslexic children and their relation to reading dysfluency |
| topic | Developmental dyslexia Reading fluency Visual word recognition Directed functional connectivity Directed transfer function |
| url | http://www.sciencedirect.com/science/article/pii/S187892931630055X |
| work_keys_str_mv | AT gojkozaric alteredpatternsofdirectedconnectivitywithinthereadingnetworkofdyslexicchildrenandtheirrelationtoreadingdysfluency AT joaomcorreia alteredpatternsofdirectedconnectivitywithinthereadingnetworkofdyslexicchildrenandtheirrelationtoreadingdysfluency AT gorkafragagonzalez alteredpatternsofdirectedconnectivitywithinthereadingnetworkofdyslexicchildrenandtheirrelationtoreadingdysfluency AT jurgentijms alteredpatternsofdirectedconnectivitywithinthereadingnetworkofdyslexicchildrenandtheirrelationtoreadingdysfluency AT maurtiswvandermolen alteredpatternsofdirectedconnectivitywithinthereadingnetworkofdyslexicchildrenandtheirrelationtoreadingdysfluency AT leoblomert alteredpatternsofdirectedconnectivitywithinthereadingnetworkofdyslexicchildrenandtheirrelationtoreadingdysfluency AT milenebonte alteredpatternsofdirectedconnectivitywithinthereadingnetworkofdyslexicchildrenandtheirrelationtoreadingdysfluency |