Dual-modified cationic liposomes loaded with paclitaxel and survivin siRNA for targeted imaging and therapy of cancer stem cells in brain glioma

Dual-modified cationic liposomes loaded with paclitaxel and survivin siRNA for targeted imaging and therapy of cancer stem cells in brain glioma

Development of safe, efficient nanocomplex for targeted imaging and therapy of cancer stem cells in brain glioma has become a great challenge. Herein, a low-density lipoprotein receptor-related protein and a RNA aptamer bound CD133 were used as dual-targeting ligands to prepare dual-modified cationi...

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Bibliographic Details
Main Authors: Xiyang Sun, Ying Chen, Hui Zhao, Guanglei Qiao, Meiyang Liu, Chunlei Zhang, Daxiang Cui, Lijun Ma
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Drug Delivery
Subjects:
glioma stem cells
survivin sirna
paclitaxel
targeted imaging
targeted therapy
Online Access:http://dx.doi.org/10.1080/10717544.2018.1494225

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