Appropriate Handling, Processing and Analysis of Blood Samples Is Essential to Avoid Oxidation of Vitamin C to Dehydroascorbic Acid

Appropriate Handling, Processing and Analysis of Blood Samples Is Essential to Avoid Oxidation of Vitamin C to Dehydroascorbic Acid

Vitamin C (ascorbate) is the major water-soluble antioxidant in plasma and its oxidation to dehydroascorbic acid (DHA) has been proposed as a marker of oxidative stress in vivo. However, controversy exists in the literature around the amount of DHA detected in blood samples collected from various pa...

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Bibliographic Details
Main Authors:	Juliet M. Pullar, Simone Bayer, Anitra C. Carr
Format:	Article
Language:	English
Published:	MDPI AG 2018-02-01
Series:	Antioxidants
Subjects:	vitamin C ascorbate dehydroascorbic acid whole blood plasma EDTA heparin HPLC with electrochemical detection pneumonia cancer diabetes critically ill
Online Access:	http://www.mdpi.com/2076-3921/7/2/29

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