Meropenem Model-Informed Precision Dosing in the Treatment of Critically Ill Patients: Can We Use It?

Meropenem Model-Informed Precision Dosing in the Treatment of Critically Ill Patients: Can We Use It?

The number of pharmacokinetic (PK) models of meropenem is increasing. However, the daily role of these PK models in the clinic remains unclear, especially for critically ill patients. Therefore, we evaluated the published meropenem models on real-world ICU data to assess their suitability for use in...

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Bibliographic Details
Main Authors: Letao Li, Sebastiaan D. T. Sassen, Tim M. J. Ewoldt, Alan Abdulla, Nicole G. M. Hunfeld, Anouk E. Muller, Brenda C. M. de Winter, Henrik Endeman, Birgit C. P. Koch
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Antibiotics
Subjects:
meropenem
ICU
population pharmacokinetics
model validation
real-world patients
model-informed precision dosing
Online Access:https://www.mdpi.com/2079-6382/12/2/383

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