Dominant strictures in primary sclerosing cholangitis: A multicenter survey of clinical definitions and practices
Dominant strictures (DSs) of the biliary tree occur in approximately 50% of patients with primary sclerosing cholangitis (PSC) and may cause significant morbidity. Nevertheless, the definition and management of DSs lacks consensus. We aimed to better understand current perceptions and practices rega...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Health/LWW
2018-07-01
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| Series: | Hepatology Communications |
| Online Access: | https://doi.org/10.1002/hep4.1194 |
| _version_ | 1797715663372943360 |
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| author | Moira B. Hilscher James H. Tabibian Elizabeth J. Carey Christopher J. Gostout Keith D. Lindor |
| author_facet | Moira B. Hilscher James H. Tabibian Elizabeth J. Carey Christopher J. Gostout Keith D. Lindor |
| author_sort | Moira B. Hilscher |
| collection | DOAJ |
| description | Dominant strictures (DSs) of the biliary tree occur in approximately 50% of patients with primary sclerosing cholangitis (PSC) and may cause significant morbidity. Nevertheless, the definition and management of DSs lacks consensus. We aimed to better understand current perceptions and practices regarding PSC‐associated DSs. We conducted an anonymous, 23‐question, survey‐based study wherein electronic surveys were distributed to 131 faculty in the Division of Gastroenterology and Hepatology at the three Mayo Clinic campuses (Rochester, Scottsdale, and Jacksonville) as well as the affiliated practice network. Responses were aggregated and compared, where applicable, to practice guidelines of the American Association for the Study of Liver Diseases and European Association for the Study of the Liver. A total of 54 faculty (41.2%) completed the survey, of whom 24 (44.4%) were hepatologists, 21 (38.9%) gastroenterologists, and 9 (16.7%) advanced endoscopists. One of the major study findings was that there was heterogeneity among participants' definition, evaluation, management, and follow‐up of DSs in PSC. The majority of participant responses were in accordance with societal practice guidelines, although considerable variation was noted. Conclusion: Despite the prevalence and morbidity of DSs in PSC, clinical perceptions and practices vary widely among hepatologists, gastroenterologists, and advanced endoscopists who manage these patients, even within a single health care system. Further studies are needed to address these variations, develop general and evidence‐based consensus, and increase adherence to societal guidelines. (Hepatology Communications 2018;2:836‐844) |
| first_indexed | 2024-03-12T08:11:00Z |
| format | Article |
| id | doaj.art-aa25036b9c4a4c70b1ad2d18a563eed9 |
| institution | Directory Open Access Journal |
| issn | 2471-254X |
| language | English |
| last_indexed | 2024-03-12T08:11:00Z |
| publishDate | 2018-07-01 |
| publisher | Wolters Kluwer Health/LWW |
| record_format | Article |
| series | Hepatology Communications |
| spelling | doaj.art-aa25036b9c4a4c70b1ad2d18a563eed92023-09-02T19:10:03ZengWolters Kluwer Health/LWWHepatology Communications2471-254X2018-07-012783684410.1002/hep4.1194Dominant strictures in primary sclerosing cholangitis: A multicenter survey of clinical definitions and practicesMoira B. Hilscher0James H. Tabibian1Elizabeth J. Carey2Christopher J. Gostout3Keith D. Lindor4Division of Gastroenterology and HepatologyMayo ClinicRochester MNDivision of Gastroenterology and HepatologyMayo ClinicRochester MNDivision of Gastroenterology and HepatologyMayo ClinicScottsdale AZDivision of Gastroenterology and HepatologyMayo ClinicRochester MNDivision of Gastroenterology and HepatologyMayo ClinicScottsdale AZDominant strictures (DSs) of the biliary tree occur in approximately 50% of patients with primary sclerosing cholangitis (PSC) and may cause significant morbidity. Nevertheless, the definition and management of DSs lacks consensus. We aimed to better understand current perceptions and practices regarding PSC‐associated DSs. We conducted an anonymous, 23‐question, survey‐based study wherein electronic surveys were distributed to 131 faculty in the Division of Gastroenterology and Hepatology at the three Mayo Clinic campuses (Rochester, Scottsdale, and Jacksonville) as well as the affiliated practice network. Responses were aggregated and compared, where applicable, to practice guidelines of the American Association for the Study of Liver Diseases and European Association for the Study of the Liver. A total of 54 faculty (41.2%) completed the survey, of whom 24 (44.4%) were hepatologists, 21 (38.9%) gastroenterologists, and 9 (16.7%) advanced endoscopists. One of the major study findings was that there was heterogeneity among participants' definition, evaluation, management, and follow‐up of DSs in PSC. The majority of participant responses were in accordance with societal practice guidelines, although considerable variation was noted. Conclusion: Despite the prevalence and morbidity of DSs in PSC, clinical perceptions and practices vary widely among hepatologists, gastroenterologists, and advanced endoscopists who manage these patients, even within a single health care system. Further studies are needed to address these variations, develop general and evidence‐based consensus, and increase adherence to societal guidelines. (Hepatology Communications 2018;2:836‐844)https://doi.org/10.1002/hep4.1194 |
| spellingShingle | Moira B. Hilscher James H. Tabibian Elizabeth J. Carey Christopher J. Gostout Keith D. Lindor Dominant strictures in primary sclerosing cholangitis: A multicenter survey of clinical definitions and practices Hepatology Communications |
| title | Dominant strictures in primary sclerosing cholangitis: A multicenter survey of clinical definitions and practices |
| title_full | Dominant strictures in primary sclerosing cholangitis: A multicenter survey of clinical definitions and practices |
| title_fullStr | Dominant strictures in primary sclerosing cholangitis: A multicenter survey of clinical definitions and practices |
| title_full_unstemmed | Dominant strictures in primary sclerosing cholangitis: A multicenter survey of clinical definitions and practices |
| title_short | Dominant strictures in primary sclerosing cholangitis: A multicenter survey of clinical definitions and practices |
| title_sort | dominant strictures in primary sclerosing cholangitis a multicenter survey of clinical definitions and practices |
| url | https://doi.org/10.1002/hep4.1194 |
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