Heterogeneity of obesity phenotypes in relation to cardiovascular risk

Obesity is associated with numerous metabolic disorders, the development and progression of a wide range of conditions and diseases, primarily cardiovascular disease and type 2 diabetes. One of the widely discussed phenomena of the association of obesity with cardiovascular diseases, their complicat...

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Main Authors: М. A. Druzhilov, Т. Yu. Kuznetsova
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2019-03-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/809
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author М. A. Druzhilov
Т. Yu. Kuznetsova
author_facet М. A. Druzhilov
Т. Yu. Kuznetsova
author_sort М. A. Druzhilov
collection DOAJ
description Obesity is associated with numerous metabolic disorders, the development and progression of a wide range of conditions and diseases, primarily cardiovascular disease and type 2 diabetes. One of the widely discussed phenomena of the association of obesity with cardiovascular diseases, their complications and mortality is the phenomenon of “heterogeneity of obesity phenotypes in relation to cardiovascular risk”. Currently, two main phenotypes have been identified — metabolically healthy and metabolically unhealthy obesity. At the same time, not only the expediency of separation, but also the existence of this phenotype is widely discussed today. The article provides an overview of existing approaches to the verification of metabolic phenotypes of obesity and data relating to the epidemiology and the association of metabolically healthy obesity with the risk of cardiovascular diseases and death, and also discusses the factors that determine the features of the obesity phenotype.
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spelling doaj.art-aa278734c689493c9cd7a71cb5aa86302024-10-17T12:21:37Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252019-03-0118116116710.15829/1728-8800-2019-1-161-167604Heterogeneity of obesity phenotypes in relation to cardiovascular riskМ. A. Druzhilov0Т. Yu. Kuznetsova1Industrial hospital of the Federal Security Service Administration of Russia in the Republic of KareliaPetrozavodsk State UniversityObesity is associated with numerous metabolic disorders, the development and progression of a wide range of conditions and diseases, primarily cardiovascular disease and type 2 diabetes. One of the widely discussed phenomena of the association of obesity with cardiovascular diseases, their complications and mortality is the phenomenon of “heterogeneity of obesity phenotypes in relation to cardiovascular risk”. Currently, two main phenotypes have been identified — metabolically healthy and metabolically unhealthy obesity. At the same time, not only the expediency of separation, but also the existence of this phenotype is widely discussed today. The article provides an overview of existing approaches to the verification of metabolic phenotypes of obesity and data relating to the epidemiology and the association of metabolically healthy obesity with the risk of cardiovascular diseases and death, and also discusses the factors that determine the features of the obesity phenotype.https://cardiovascular.elpub.ru/jour/article/view/809obesity phenotypemetabolically healthy obesityvisceral obesitycardiovascular risk
spellingShingle М. A. Druzhilov
Т. Yu. Kuznetsova
Heterogeneity of obesity phenotypes in relation to cardiovascular risk
Кардиоваскулярная терапия и профилактика
obesity phenotype
metabolically healthy obesity
visceral obesity
cardiovascular risk
title Heterogeneity of obesity phenotypes in relation to cardiovascular risk
title_full Heterogeneity of obesity phenotypes in relation to cardiovascular risk
title_fullStr Heterogeneity of obesity phenotypes in relation to cardiovascular risk
title_full_unstemmed Heterogeneity of obesity phenotypes in relation to cardiovascular risk
title_short Heterogeneity of obesity phenotypes in relation to cardiovascular risk
title_sort heterogeneity of obesity phenotypes in relation to cardiovascular risk
topic obesity phenotype
metabolically healthy obesity
visceral obesity
cardiovascular risk
url https://cardiovascular.elpub.ru/jour/article/view/809
work_keys_str_mv AT madruzhilov heterogeneityofobesityphenotypesinrelationtocardiovascularrisk
AT tyukuznetsova heterogeneityofobesityphenotypesinrelationtocardiovascularrisk