Multicenter Study of Benign Thyroid Nodules with Radiofrequency Ablation: Results of 762 Cases over 4 Years in Taiwan
Background: To evaluate the effectiveness and safety of radiofrequency ablation (RFA) treatment for benign thyroid nodules (BTNs) in five medical centers in Taiwan. Methods: From April 2016 to July 2020, 762 patients underwent ultrasound guided RFA treatment of 826 benign thyroid nodules at five med...
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MDPI AG
2022-01-01
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| Series: | Journal of Personalized Medicine |
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| Online Access: | https://www.mdpi.com/2075-4426/12/1/63 |
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| author | Wei-Che Lin Cheng-Kang Wang Wen-Hung Wang Chi-Yu Kuo Pi-Ling Chiang An-Ni Lin Jung Hwan Baek Ming-Hsun Wu Kai-Lun Cheng |
| author_facet | Wei-Che Lin Cheng-Kang Wang Wen-Hung Wang Chi-Yu Kuo Pi-Ling Chiang An-Ni Lin Jung Hwan Baek Ming-Hsun Wu Kai-Lun Cheng |
| author_sort | Wei-Che Lin |
| collection | DOAJ |
| description | Background: To evaluate the effectiveness and safety of radiofrequency ablation (RFA) treatment for benign thyroid nodules (BTNs) in five medical centers in Taiwan. Methods: From April 2016 to July 2020, 762 patients underwent ultrasound guided RFA treatment of 826 benign thyroid nodules at five medical centers in Taiwan. The RFA procedure was performed by radiologists, otolaryngologists, or surgeons. Patients were grouped into three subgroups according to the initial volume of BTNs. The volume reduction ratio (VRR) of each nodule, and complications were analyzed at 1, 3, and 6 months after RFA treatment and the three groups compared. Results: The large nodular group showed greater VRR compared to the other two groups at first 1-month follow-up. At 6-months follow-up, there was no significant difference of VRR among the three groups. Goiters with difference in size can attain a successful VRR (>50%) although different specialists demonstrated variable VRR after 6-months follow-up. A total of 40 (4.8%) complications were reported. All patients recovered spontaneously without surgery intervention. Conclusions: The reliability and safety of RFA for benign thyroid nodules had been established. RFA has gradually become an alternative to surgery in the treatment of benign thyroid nodules in Taiwan. |
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| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-10T01:09:34Z |
| publishDate | 2022-01-01 |
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| series | Journal of Personalized Medicine |
| spelling | doaj.art-aa2877d97dd64c798884bb7cc81b02d72023-11-23T14:19:57ZengMDPI AGJournal of Personalized Medicine2075-44262022-01-011216310.3390/jpm12010063Multicenter Study of Benign Thyroid Nodules with Radiofrequency Ablation: Results of 762 Cases over 4 Years in TaiwanWei-Che Lin0Cheng-Kang Wang1Wen-Hung Wang2Chi-Yu Kuo3Pi-Ling Chiang4An-Ni Lin5Jung Hwan Baek6Ming-Hsun Wu7Kai-Lun Cheng8Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833, TaiwanDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833, TaiwanDepartment of Otolaryngology, Cathay General Hospital, Taipei 106, TaiwanDepartment of Surgery, MacKay Memorial Hospital, Taipei 104, TaiwanDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833, TaiwanDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833, TaiwanDepartment of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, KoreaDepartment of Surgery, National Taiwan University Hospital, Taipei 100, TaiwanDepartment of Medical Imaging, Chung Shan Medical University Hospital, Taichung 402, TaiwanBackground: To evaluate the effectiveness and safety of radiofrequency ablation (RFA) treatment for benign thyroid nodules (BTNs) in five medical centers in Taiwan. Methods: From April 2016 to July 2020, 762 patients underwent ultrasound guided RFA treatment of 826 benign thyroid nodules at five medical centers in Taiwan. The RFA procedure was performed by radiologists, otolaryngologists, or surgeons. Patients were grouped into three subgroups according to the initial volume of BTNs. The volume reduction ratio (VRR) of each nodule, and complications were analyzed at 1, 3, and 6 months after RFA treatment and the three groups compared. Results: The large nodular group showed greater VRR compared to the other two groups at first 1-month follow-up. At 6-months follow-up, there was no significant difference of VRR among the three groups. Goiters with difference in size can attain a successful VRR (>50%) although different specialists demonstrated variable VRR after 6-months follow-up. A total of 40 (4.8%) complications were reported. All patients recovered spontaneously without surgery intervention. Conclusions: The reliability and safety of RFA for benign thyroid nodules had been established. RFA has gradually become an alternative to surgery in the treatment of benign thyroid nodules in Taiwan.https://www.mdpi.com/2075-4426/12/1/63goiterradiofrequency ablationTaiwanthyroid glandultrasound |
| spellingShingle | Wei-Che Lin Cheng-Kang Wang Wen-Hung Wang Chi-Yu Kuo Pi-Ling Chiang An-Ni Lin Jung Hwan Baek Ming-Hsun Wu Kai-Lun Cheng Multicenter Study of Benign Thyroid Nodules with Radiofrequency Ablation: Results of 762 Cases over 4 Years in Taiwan Journal of Personalized Medicine goiter radiofrequency ablation Taiwan thyroid gland ultrasound |
| title | Multicenter Study of Benign Thyroid Nodules with Radiofrequency Ablation: Results of 762 Cases over 4 Years in Taiwan |
| title_full | Multicenter Study of Benign Thyroid Nodules with Radiofrequency Ablation: Results of 762 Cases over 4 Years in Taiwan |
| title_fullStr | Multicenter Study of Benign Thyroid Nodules with Radiofrequency Ablation: Results of 762 Cases over 4 Years in Taiwan |
| title_full_unstemmed | Multicenter Study of Benign Thyroid Nodules with Radiofrequency Ablation: Results of 762 Cases over 4 Years in Taiwan |
| title_short | Multicenter Study of Benign Thyroid Nodules with Radiofrequency Ablation: Results of 762 Cases over 4 Years in Taiwan |
| title_sort | multicenter study of benign thyroid nodules with radiofrequency ablation results of 762 cases over 4 years in taiwan |
| topic | goiter radiofrequency ablation Taiwan thyroid gland ultrasound |
| url | https://www.mdpi.com/2075-4426/12/1/63 |
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