Genomic profile of metastatic breast cancer patient-derived xenografts established using percutaneous biopsy

Genomic profile of metastatic breast cancer patient-derived xenografts established using percutaneous biopsy

Abstract Background Metastatic breast cancer (mBC) is a complex and life-threatening disease and although it is difficult to cure, patients can benefit from sequential anticancer treatment, including endocrine therapy, targeted therapy and cytotoxic chemotherapy. The patient-derived xenograft (PDX)...

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Bibliographic Details
Main Authors: Seongyeong Kim, Dongjin Shin, Ahrum Min, Minjung Kim, Deukchae Na, Han-Byeol Lee, Han Suk Ryu, Yaewon Yang, Go-Un Woo, Kyung-Hun Lee, Dae-Won Lee, Tae-Yong Kim, Charles Lee, Seock-Ah Im, Jong-Il Kim
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Translational Medicine
Subjects:
Metastatic breast cancer
Patient-derived xenograft
Whole-exome sequencing
Online Access:https://doi.org/10.1186/s12967-020-02607-2

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