The ADA*2 allele of the adenosine deaminase gene (20q13.11) and recurrent spontaneous abortions: an age-dependent association

The ADA*2 allele of the adenosine deaminase gene (20q13.11) and recurrent spontaneous abortions: an age-dependent association

OBJECTIVE: Adenosine deaminase acts on adenosine and deoxyadenosine metabolism and modulates the immune response. The adenosine deaminase G22A polymorphism (20q.11.33) influences the level of adenosine deaminase enzyme expression, which seems to play a key role in maintaining pregnancy. The adenosin...

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Bibliographic Details
Main Authors: Daniela Prudente Teixeira Nunes, Lígia Cosentino Junqueira Franco Spegiorin, Cinara Cássia Brandão de Mattos, Antonio Helio Oliani, Denise Cristina Mós Vaz-Oliani, Luiz Carlos de Mattos
Format: Article
Language:English
Published: Elsevier España 2011-01-01
Series:Clinics
Subjects:
Adenosine deaminase
Recurrent spontaneous abortions
ADA gene
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011001100013

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