Caprine arthritis and encephalitis virus infection in goats of Bangladesh: Serological detection and its associated risk factors
Background and Aim: Caprine arthritis and encephalitis (CAE) is a multisystemic persistent viral disease of goat that causes significant economic losses to the farmers and livestock sector. However, no information in this country is available regarding CAE virus (CAEV) infection. Therefore, this stu...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Veterinary World
2023-11-01
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| Series: | Veterinary World |
| Subjects: | |
| Online Access: | https://www.veterinaryworld.org/Vol.16/November-2023/11.pdf |
| _version_ | 1827765129273409536 |
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| author | Md. Habibur Rahma Sonia Akther Md. Shahin Alam Md. Zulfekar Ali Sadek Ahmed |
| author_facet | Md. Habibur Rahma Sonia Akther Md. Shahin Alam Md. Zulfekar Ali Sadek Ahmed |
| author_sort | Md. Habibur Rahma |
| collection | DOAJ |
| description | Background and Aim: Caprine arthritis and encephalitis (CAE) is a multisystemic persistent viral disease of goat that causes significant economic losses to the farmers and livestock sector. However, no information in this country is available regarding CAE virus (CAEV) infection. Therefore, this study aimed to estimate the seroprevalence of CAEV infection among the goat population in the selected goat-prone districts in Bangladesh and to identify the associated risk factors of the disease.
Materials and Methods: From July 2021 to June 2022, 446 goat serum samples were randomly collected from the study area. Goat owners were interviewed using a pretested questionnaire to determine the risk factors. A commercial indirect enzyme-linked immunosorbent assay kit was used to screen blood serum for CAEV antibodies. Logistic regression models were used to analyze risk factors and serological data to identify the potential risk factors.
Results: Out of 446 serum samples, 19 samples were seropositive against CAEV. The overall seroprevalence was 4.26% (95% confidence interval [CI]: 2.58–6.57). The multivariable logistic regression model identified sex (Female; odds ratio [OR]: 3.98; 95% CI: 1.13–13.95), animal age (12–48 months; OR: 4.93, 95% CI: 0.63–38.13), and biosecurity status (Poor biosecurity; OR: 1.66, 95% CI: 0.46–5.92) as potential risk factors for CAEV seropositivity.
Conclusion: This study revealed the serological detection of CAEV in Bangladeshi goats where seroprevalence is found to be relatively low. To eradicate the disease, screening and culling of infected goats from the herd might be implemented. |
| first_indexed | 2024-03-11T11:15:44Z |
| format | Article |
| id | doaj.art-aa2d74a950a342e787d2a8942c872708 |
| institution | Directory Open Access Journal |
| issn | 0972-8988 2231-0916 |
| language | English |
| last_indexed | 2024-03-11T11:15:44Z |
| publishDate | 2023-11-01 |
| publisher | Veterinary World |
| record_format | Article |
| series | Veterinary World |
| spelling | doaj.art-aa2d74a950a342e787d2a8942c8727082023-11-11T06:36:04ZengVeterinary WorldVeterinary World0972-89882231-09162023-11-0116112256226210.14202/vetworld.2023.2256-2262Caprine arthritis and encephalitis virus infection in goats of Bangladesh: Serological detection and its associated risk factorsMd. Habibur Rahma0https://orcid.org/0000-0002-3221-2142Sonia Akther1https://orcid.org/0000-0002-5064-2154Md. Shahin Alam2https://orcid.org/0000-0003-4129-3199Md. Zulfekar Ali3https://orcid.org/0000-0002-3971-8699Sadek Ahmed4https://orcid.org/0000-0002-9680-7372Goat Production Research Division, Bangladesh Livestock Research Institute, Savar, Dhaka 1341, Bangladesh; Faridpur Regional Station, Bangladesh Livestock Research Institute, Faridpur, Bangladesh.Sheep Production Research Division, Bangladesh Livestock Research Institute, Savar, Dhaka 1341, Bangladesh.Animal Health Research Division, Bangladesh Livestock Research Institute, Savar, Dhaka 1341, Bangladesh.Animal Health Research Division, Bangladesh Livestock Research Institute, Savar, Dhaka 1341, Bangladesh.Goat Production Research Division, Bangladesh Livestock Research Institute, Savar, Dhaka 1341, Bangladesh; Black Bengal Goat Conservation and Development Research Project, Bangladesh Livestock Research Institute, Savar, Dhaka 1341, Bangladesh.Background and Aim: Caprine arthritis and encephalitis (CAE) is a multisystemic persistent viral disease of goat that causes significant economic losses to the farmers and livestock sector. However, no information in this country is available regarding CAE virus (CAEV) infection. Therefore, this study aimed to estimate the seroprevalence of CAEV infection among the goat population in the selected goat-prone districts in Bangladesh and to identify the associated risk factors of the disease. Materials and Methods: From July 2021 to June 2022, 446 goat serum samples were randomly collected from the study area. Goat owners were interviewed using a pretested questionnaire to determine the risk factors. A commercial indirect enzyme-linked immunosorbent assay kit was used to screen blood serum for CAEV antibodies. Logistic regression models were used to analyze risk factors and serological data to identify the potential risk factors. Results: Out of 446 serum samples, 19 samples were seropositive against CAEV. The overall seroprevalence was 4.26% (95% confidence interval [CI]: 2.58–6.57). The multivariable logistic regression model identified sex (Female; odds ratio [OR]: 3.98; 95% CI: 1.13–13.95), animal age (12–48 months; OR: 4.93, 95% CI: 0.63–38.13), and biosecurity status (Poor biosecurity; OR: 1.66, 95% CI: 0.46–5.92) as potential risk factors for CAEV seropositivity. Conclusion: This study revealed the serological detection of CAEV in Bangladeshi goats where seroprevalence is found to be relatively low. To eradicate the disease, screening and culling of infected goats from the herd might be implemented.https://www.veterinaryworld.org/Vol.16/November-2023/11.pdfbangladeshcaprine arthritis and encephalitisenzyme-linked immunosorbent assaygoatrisk factorsseroprevalence |
| spellingShingle | Md. Habibur Rahma Sonia Akther Md. Shahin Alam Md. Zulfekar Ali Sadek Ahmed Caprine arthritis and encephalitis virus infection in goats of Bangladesh: Serological detection and its associated risk factors Veterinary World bangladesh caprine arthritis and encephalitis enzyme-linked immunosorbent assay goat risk factors seroprevalence |
| title | Caprine arthritis and encephalitis virus infection in goats of Bangladesh: Serological detection and its associated risk factors |
| title_full | Caprine arthritis and encephalitis virus infection in goats of Bangladesh: Serological detection and its associated risk factors |
| title_fullStr | Caprine arthritis and encephalitis virus infection in goats of Bangladesh: Serological detection and its associated risk factors |
| title_full_unstemmed | Caprine arthritis and encephalitis virus infection in goats of Bangladesh: Serological detection and its associated risk factors |
| title_short | Caprine arthritis and encephalitis virus infection in goats of Bangladesh: Serological detection and its associated risk factors |
| title_sort | caprine arthritis and encephalitis virus infection in goats of bangladesh serological detection and its associated risk factors |
| topic | bangladesh caprine arthritis and encephalitis enzyme-linked immunosorbent assay goat risk factors seroprevalence |
| url | https://www.veterinaryworld.org/Vol.16/November-2023/11.pdf |
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