Dynamic sex chromosome expression in Drosophila male germ cells
Sex chromosome gene content and expression is unusual. Here the authors use single cell RNA-Seq on Drosophila larvae to demonstrate that the single X and pair of 4th chromosomes are specifically inactivated in primary spermatocytes, while genes on the single Y chromosome become maximally active in p...
Main Authors: | Sharvani Mahadevaraju, Justin M. Fear, Miriam Akeju, Brian J. Galletta, Mara M. L. S. Pinheiro, Camila C. Avelino, Diogo C. Cabral-de-Mello, Katie Conlon, Stafania Dell’Orso, Zelalem Demere, Kush Mansuria, Carolina A. Mendonça, Octavio M. Palacios-Gimenez, Eli Ross, Max Savery, Kevin Yu, Harold E. Smith, Vittorio Sartorelli, Haiwang Yang, Nasser M. Rusan, Maria D. Vibranovski, Erika Matunis, Brian Oliver |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-02-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-20897-y |
Similar Items
-
Germ Cell-less Promotes Centrosome Segregation to Induce Germ Cell Formation
by: Dorothy A. Lerit, et al.
Published: (2017-01-01) -
Newly Characterized Region of CP190 Associates with Microtubules and Mediates Proper Spindle Morphology in Drosophila Stem Cells.
by: Karen M Plevock, et al.
Published: (2015-01-01) -
Protocols to generate and isolate mouse myogenic progenitors both in vitro and in vivo
by: Mamduh Khateb, et al.
Published: (2023-03-01) -
Integrating single-cell transcriptomes, chromatin accessibility, and multiomics analysis of mesoderm-induced embryonic stem cells
by: Kyung Dae Ko, et al.
Published: (2023-06-01) -
Male Germ Cell Telomeres and Chemical Pollutants
by: Gabriella Chieffi Baccari, et al.
Published: (2023-04-01)