Research progress of integrated stress response in pathogenesis of Alzheimer's disease

Research progress of integrated stress response in pathogenesis of Alzheimer's disease

Integrated stress response (ISR) is a cellular adaptive response induced by stress, which is strictly regulated by multiple phosphokinases, phosphatases and other proteins to maintain protein homeostasis. Studies have shown that ISR is abnormally activated in Alzheimer's disease, and targeted r...

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Bibliographic Details
Main Authors: SUN Hui, JIN Hongfu, GUO Shenrui, FENG Yiyuan, YIN Yafu, WANG Hui, CHENG Weiwei
Format: Article
Language:zho
Published: Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science) 2023-06-01
Series:Shanghai Jiaotong Daxue xuebao. Yixue ban
Subjects:
integrated stress response
alzheimer disease
integrated stress response inhibitor
protein homeostasis
Online Access:https://xuebao.shsmu.edu.cn/article/2023/1674-8115/1674-8115-2023-43-6-755.shtml

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