Chagasic cardiomyopathy is marked by a unique signature of activated CD4+ T cells

Chagasic cardiomyopathy is marked by a unique signature of activated CD4+ T cells

Abstract Chagas disease is a neglected tropical disease in Latin America and an imported emerging disease worldwide. Chronic Chagas disease cardiomyopathy (CCC) is the most prominent clinical form and can lead to heart failure, thromboembolism, and sudden death. While previous reports have supported...

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Bibliographic Details
Main Authors: Gregório Guilherme Almeida, Inga Rimkute, Isabela Natália Pascoal Campos do Vale, Thomas Liechti, Priscilla Miranda Henriques, Ester Roffe, Fernanda Fortes de Araújo, Manoel Otávio da Costa Rocha, Silvana Maria Elói Santos, Olindo Assis Martins-Filho, Dragana Jankovic, Alan Sher, Andrea Teixeira-Carvalho, Mario Roederer, Lis Ribeiro do Valle Antonelli
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Journal of Translational Medicine
Subjects:
Chagas disease
Trypanosoma cruzi
Cardiomyopathy
CD4+ T cells
Multifunctional
Cytotoxic
Online Access:https://doi.org/10.1186/s12967-022-03761-5

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