Enhancement of endogenous midbrain neurogenesis by microneurotrophin BNN-20 after neural progenitor grafting in a mouse model of nigral degeneration

Enhancement of endogenous midbrain neurogenesis by microneurotrophin BNN-20 after neural progenitor grafting in a mouse model of nigral degeneration

[INLINE:1] We have previously shown the neuroprotective and pro-neurogenic activity of microneurotrophin BNN-20 in the substantia nigra of the “weaver” mouse, a model of progressive nigrostriatal degeneration. Here, we extended our investigation in two clinically-relevant ways. First, we assessed th...

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Bibliographic Details
Main Authors: Theodora Mourtzi, Nasia Antoniou, Christina Dimitriou, Panagiotis Gkaravelas, Georgia Athanasopoulou, Panagiota Nti Kostantzo, Olga Stathi, Efthymia Theodorou, Maria Anesti, Rebecca Matsas, Fevronia Angelatou, Georgia Kouroupi, Ilias Kazanis
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Neural Regeneration Research
Subjects:
adult neurogenesis; bnn-20; brain-derived neurotrophic factor; cell replacement; induced pluripotent stem cells (ipscs); neurotrophic factors; parkinson’s disease; substantia
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=6;spage=1318;epage=1324;aulast=Mourtzi

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