Clinical characteristics and risk factors of active bleeding in colonic angiodysplasia among the Taiwanese
Background: Colonic angiodysplasia (AGD) is a common cause of gastrointestinal bleeding. However, information on the characteristics and prevalence of colonic AGD is limited. We determined the clinical features of and risk factors for active bleeding in colonic AGD in a Taiwanese population. Methods...
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| Format: | Article |
| Language: | English |
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Elsevier
2019-05-01
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| Series: | Journal of the Formosan Medical Association |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0929664618304108 |
| _version_ | 1818310058655612928 |
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| author | Yi-Yen Tsai Bao-Chung Chen Yu-Ching Chou Jung-Chun Lin Hsuan-Hwai Lin Hsin-Hung Huang Tien-Yu Huang |
| author_facet | Yi-Yen Tsai Bao-Chung Chen Yu-Ching Chou Jung-Chun Lin Hsuan-Hwai Lin Hsin-Hung Huang Tien-Yu Huang |
| author_sort | Yi-Yen Tsai |
| collection | DOAJ |
| description | Background: Colonic angiodysplasia (AGD) is a common cause of gastrointestinal bleeding. However, information on the characteristics and prevalence of colonic AGD is limited. We determined the clinical features of and risk factors for active bleeding in colonic AGD in a Taiwanese population. Methods: From February 2007 to December 2016, 13,047 patients undergoing 16,760 colonoscopies at the Tri-Service General Hospital were included in this study. Eighty-four patients were diagnosed with AGD. We conducted a retrospective study by analyzing the medical records of these patients. The clinical features and endoscopic findings were evaluated. Furthermore, we distinguished colonic AGD into bleeding and non-bleeding types and identified the risk factors for bleeding in colonic AGD. Results: In our study, the prevalence of colonic AGD was 0.6% among all patients who received colonoscopy. Among patients with colonic AGD, we found that many were aged; in all, 58.3% of patients with colonic AGD were older than 65 years. More than half of the patients had hypertensive cardiovascular disease (53.6%) and the AGD lesions were predominantly located in the left-sided colon (41.7%). We analyzed several factors to identify those associated with bleeding colonic AGD. Our results indicated that age (p < 0.001), hypertension (p = 0.020), atrial fibrillation (p = 0.027), and in-patient status (p = 0.006) were significant factors associated with active bleeding lesions. On multivariate analysis, old age was the only significant risk factor. Conclusion: Angiodysplastic lesions in Taiwanese patients were predominantly identified in the left-sided colon. Old age was an independent risk factor associated with active bleeding in colonic angiodysplasia. Keywords: Colonic angiodysplasia, Bleeding, Risk factor |
| first_indexed | 2024-12-13T07:40:02Z |
| format | Article |
| id | doaj.art-aa3494003faa4ae7ba0a0f47f4b28e07 |
| institution | Directory Open Access Journal |
| issn | 0929-6646 |
| language | English |
| last_indexed | 2024-12-13T07:40:02Z |
| publishDate | 2019-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of the Formosan Medical Association |
| spelling | doaj.art-aa3494003faa4ae7ba0a0f47f4b28e072022-12-21T23:54:59ZengElsevierJournal of the Formosan Medical Association0929-66462019-05-011185876882Clinical characteristics and risk factors of active bleeding in colonic angiodysplasia among the TaiwaneseYi-Yen Tsai0Bao-Chung Chen1Yu-Ching Chou2Jung-Chun Lin3Hsuan-Hwai Lin4Hsin-Hung Huang5Tien-Yu Huang6National Defense Medical Center, Taipei, TaiwanDivision of Gastroenterology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanNational Defense Medical Center, Taipei, TaiwanDivision of Gastroenterology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanDivision of Gastroenterology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanDivision of Gastroenterology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanDivision of Gastroenterology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan; Taiwan Association for the Study of Small Intestinal Diseases, Taoyuan, Taiwan; Corresponding author. Division of Gastroenterology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.Background: Colonic angiodysplasia (AGD) is a common cause of gastrointestinal bleeding. However, information on the characteristics and prevalence of colonic AGD is limited. We determined the clinical features of and risk factors for active bleeding in colonic AGD in a Taiwanese population. Methods: From February 2007 to December 2016, 13,047 patients undergoing 16,760 colonoscopies at the Tri-Service General Hospital were included in this study. Eighty-four patients were diagnosed with AGD. We conducted a retrospective study by analyzing the medical records of these patients. The clinical features and endoscopic findings were evaluated. Furthermore, we distinguished colonic AGD into bleeding and non-bleeding types and identified the risk factors for bleeding in colonic AGD. Results: In our study, the prevalence of colonic AGD was 0.6% among all patients who received colonoscopy. Among patients with colonic AGD, we found that many were aged; in all, 58.3% of patients with colonic AGD were older than 65 years. More than half of the patients had hypertensive cardiovascular disease (53.6%) and the AGD lesions were predominantly located in the left-sided colon (41.7%). We analyzed several factors to identify those associated with bleeding colonic AGD. Our results indicated that age (p < 0.001), hypertension (p = 0.020), atrial fibrillation (p = 0.027), and in-patient status (p = 0.006) were significant factors associated with active bleeding lesions. On multivariate analysis, old age was the only significant risk factor. Conclusion: Angiodysplastic lesions in Taiwanese patients were predominantly identified in the left-sided colon. Old age was an independent risk factor associated with active bleeding in colonic angiodysplasia. Keywords: Colonic angiodysplasia, Bleeding, Risk factorhttp://www.sciencedirect.com/science/article/pii/S0929664618304108 |
| spellingShingle | Yi-Yen Tsai Bao-Chung Chen Yu-Ching Chou Jung-Chun Lin Hsuan-Hwai Lin Hsin-Hung Huang Tien-Yu Huang Clinical characteristics and risk factors of active bleeding in colonic angiodysplasia among the Taiwanese Journal of the Formosan Medical Association |
| title | Clinical characteristics and risk factors of active bleeding in colonic angiodysplasia among the Taiwanese |
| title_full | Clinical characteristics and risk factors of active bleeding in colonic angiodysplasia among the Taiwanese |
| title_fullStr | Clinical characteristics and risk factors of active bleeding in colonic angiodysplasia among the Taiwanese |
| title_full_unstemmed | Clinical characteristics and risk factors of active bleeding in colonic angiodysplasia among the Taiwanese |
| title_short | Clinical characteristics and risk factors of active bleeding in colonic angiodysplasia among the Taiwanese |
| title_sort | clinical characteristics and risk factors of active bleeding in colonic angiodysplasia among the taiwanese |
| url | http://www.sciencedirect.com/science/article/pii/S0929664618304108 |
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