A Rhodococcal Transcriptional Regulatory Mechanism Detects the Common Lactone Ring of AHL Quorum-Sensing Signals and Triggers the Quorum-Quenching Response

A Rhodococcal Transcriptional Regulatory Mechanism Detects the Common Lactone Ring of AHL Quorum-Sensing Signals and Triggers the Quorum-Quenching Response

The biocontrol agent Rhodococcus erythropolis disrupts virulence of plant and human Gram-negative pathogens by catabolizing their N-acyl-homoserine lactones. This quorum-quenching activity requires the expression of the qsd (quorum-sensing signal degradation) operon, which encodes the lactonase QsdA...

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Bibliographic Details
Main Authors: Corinne Barbey, Andrea Chane, Jean-François Burini, Olivier Maillot, Annabelle Merieau, Mathias Gallique, Amélie Beury-Cirou, Yoan Konto-Ghiorghi, Marc Feuilloley, Virginie Gobert, Xavier Latour
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Microbiology
Subjects:
biocontrol
Actinobacterium
Rhodococcus
TetR-like regulator
metabolism
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02800/full

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