Toxicity Evaluation of the Naphthalen-2-yl 3,5-Dinitrobenzoate: A Drug Candidate for Alzheimer Disease

Toxicity Evaluation of the Naphthalen-2-yl 3,5-Dinitrobenzoate: A Drug Candidate for Alzheimer Disease

The presented study was designed to probe the toxicity potential of newly identified compound naphthalen-2-yl 3,5-dinitrobenzoate (SF1). Acute, subacute toxicity and teratogenicity studies were performed as per Organization of economic cooperation and development (OECD) 425, 407, and 414 test guidel...

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Bibliographic Details
Main Authors: Fareeha Anwar, Uzma Saleem, Atta-Ur Rehman, Bashir Ahmad, Matheus Froeyen, Muhammad Usman Mirza, Lee Yean Kee, Iskandar Abdullah, Sarfraz Ahmad
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
acute oral toxicity
subacute toxicity
teratogenicity
oxidative stress markers
biochemical parameters
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.607026/full

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