Postictal suppression in electroconvulsive therapy (ECT) according to sex, age, diagnosis and treatment phase
Introduction Postictal suppression (PSI) is considered a key feature for ECT’s outcomes because higher values have been correlated with clinical efficacy. However, little is known about the demographic factors influencing this parameter. Objectives To analyze the influence of sex, age, diagnosis...
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| Language: | English |
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Cambridge University Press
2021-04-01
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| Series: | European Psychiatry |
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| Online Access: | https://www.cambridge.org/core/product/identifier/S0924933821020708/type/journal_article |
| _version_ | 1827754903453302784 |
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| author | V. Llorca-Bofí E. Buil-Reiné M. Adrados-Pérez G. Torterolo M. Sánchez A. Gisbert-Solà S. Pàmpols-Pérez R. Palacios-Garrán A. Torrent I. Batalla |
| author_facet | V. Llorca-Bofí E. Buil-Reiné M. Adrados-Pérez G. Torterolo M. Sánchez A. Gisbert-Solà S. Pàmpols-Pérez R. Palacios-Garrán A. Torrent I. Batalla |
| author_sort | V. Llorca-Bofí |
| collection | DOAJ |
| description |
Introduction
Postictal suppression (PSI) is considered a key feature for ECT’s outcomes because higher values have been correlated with clinical efficacy. However, little is known about the demographic factors influencing this parameter.
Objectives
To analyze the influence of sex, age, diagnosis and treatment phase on ECT efficacy measured with PSI value.
Methods
3251 ECT sessions were performed on 182 patients during two years at a university hospital. PSI was retrospectively analyzed comparing it according to sex (male, female), age, main diagnosis (major depressive disorder [MDD], bipolar disorder [BD], schizoaffective disorder [SZA], schizophrenia [SCZ]) and treatment phase (acute [a-ECT], continuation [c-ECT], maintenance [m-ECT]).
Results
PSI values were 69.76 % (SD 17.05) in women and 70.72 % (SD 16.81) in men without differences between sexes (F=0.979; p=0.607). PSI was correlated with age (r=-0.058; p=0.031). MDD PSI was 70.01 % (SD 16.88), for BD it was 69.48 % (SD 17.00), for SZA it was 68.62 % (SD 17.39), and for SCZ it was 70.73 % (SD 17.18), without differences between diagnosis (F=1.085; p=0.141). According to treatment phase, PSI in the a-ECT was 72.26 % (SD 16.43), in the c-ECT it was 67.83 % (SD 17.53), and in the m-ECT it was 68.47 % (SD 17.02), without differences between phases (F=0.901; p=0.915).
Conclusions
Although there exist statistically significant association between age and PSI it is a negligible correlation with no clinical relevance. Thus, we conclude that neither sex nor age, nor diagnosis, nor treatment phase seem to influence PSI to a relevant degree.
Disclosure
No significant relationships.
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| first_indexed | 2024-03-11T07:55:55Z |
| format | Article |
| id | doaj.art-aa3b4b4b16a64fd0a8e925c7fc070f05 |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-03-11T07:55:55Z |
| publishDate | 2021-04-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-aa3b4b4b16a64fd0a8e925c7fc070f052023-11-17T05:05:45ZengCambridge University PressEuropean Psychiatry0924-93381778-35852021-04-0164S782S78210.1192/j.eurpsy.2021.2070Postictal suppression in electroconvulsive therapy (ECT) according to sex, age, diagnosis and treatment phaseV. Llorca-Bofí0E. Buil-Reiné1M. Adrados-Pérez2G. Torterolo3M. Sánchez4A. Gisbert-Solà5S. Pàmpols-Pérez6R. Palacios-Garrán7A. Torrent8I. Batalla9Psychiatry Department, HU Santa Maria, Lleida, SpainPsychiatry Department, HU Santa Maria, Lleida, SpainPsychiatry Department, HU Santa Maria, Lleida, SpainPsychiatry Department, HU Santa Maria, Lleida, SpainPsychiatry Department, HU Santa Maria, Lleida, SpainPsychiatry Department, HU Santa Maria, Lleida, SpainPsychiatry Department, HU Santa Maria, Lleida, SpainPsychiatry Department, HU Santa Maria, Lleida, SpainPsychiatry Department, HU Santa Maria, Lleida, SpainPsychiatry Department, HU Santa Maria, Lleida, Spain Introduction Postictal suppression (PSI) is considered a key feature for ECT’s outcomes because higher values have been correlated with clinical efficacy. However, little is known about the demographic factors influencing this parameter. Objectives To analyze the influence of sex, age, diagnosis and treatment phase on ECT efficacy measured with PSI value. Methods 3251 ECT sessions were performed on 182 patients during two years at a university hospital. PSI was retrospectively analyzed comparing it according to sex (male, female), age, main diagnosis (major depressive disorder [MDD], bipolar disorder [BD], schizoaffective disorder [SZA], schizophrenia [SCZ]) and treatment phase (acute [a-ECT], continuation [c-ECT], maintenance [m-ECT]). Results PSI values were 69.76 % (SD 17.05) in women and 70.72 % (SD 16.81) in men without differences between sexes (F=0.979; p=0.607). PSI was correlated with age (r=-0.058; p=0.031). MDD PSI was 70.01 % (SD 16.88), for BD it was 69.48 % (SD 17.00), for SZA it was 68.62 % (SD 17.39), and for SCZ it was 70.73 % (SD 17.18), without differences between diagnosis (F=1.085; p=0.141). According to treatment phase, PSI in the a-ECT was 72.26 % (SD 16.43), in the c-ECT it was 67.83 % (SD 17.53), and in the m-ECT it was 68.47 % (SD 17.02), without differences between phases (F=0.901; p=0.915). Conclusions Although there exist statistically significant association between age and PSI it is a negligible correlation with no clinical relevance. Thus, we conclude that neither sex nor age, nor diagnosis, nor treatment phase seem to influence PSI to a relevant degree. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S0924933821020708/type/journal_articleElectroconvulsive therapypostictal suppression |
| spellingShingle | V. Llorca-Bofí E. Buil-Reiné M. Adrados-Pérez G. Torterolo M. Sánchez A. Gisbert-Solà S. Pàmpols-Pérez R. Palacios-Garrán A. Torrent I. Batalla Postictal suppression in electroconvulsive therapy (ECT) according to sex, age, diagnosis and treatment phase European Psychiatry Electroconvulsive therapy postictal suppression |
| title | Postictal suppression in electroconvulsive therapy (ECT) according to sex, age, diagnosis and treatment phase |
| title_full | Postictal suppression in electroconvulsive therapy (ECT) according to sex, age, diagnosis and treatment phase |
| title_fullStr | Postictal suppression in electroconvulsive therapy (ECT) according to sex, age, diagnosis and treatment phase |
| title_full_unstemmed | Postictal suppression in electroconvulsive therapy (ECT) according to sex, age, diagnosis and treatment phase |
| title_short | Postictal suppression in electroconvulsive therapy (ECT) according to sex, age, diagnosis and treatment phase |
| title_sort | postictal suppression in electroconvulsive therapy ect according to sex age diagnosis and treatment phase |
| topic | Electroconvulsive therapy postictal suppression |
| url | https://www.cambridge.org/core/product/identifier/S0924933821020708/type/journal_article |
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