Computationally inferred cell-type specific epigenome-wide DNA methylation analysis unveils distinct methylation patterns among immune cells for HIV infection in three cohorts.

Computationally inferred cell-type specific epigenome-wide DNA methylation analysis unveils distinct methylation patterns among immune cells for HIV infection in three cohorts.

<h4>Background</h4>Epigenome-wide association studies (EWAS) have identified CpG sites associated with HIV infection in blood cells in bulk, which offer limited knowledge of cell-type specific methylation patterns associated with HIV infection. In this study, we aim to identify different...

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Bibliographic Details
Main Authors: Xinyu Zhang, Ying Hu, Ral E Vandenhoudt, Chunhua Yan, Vincent C Marconi, Mardge H Cohen, Zuoheng Wang, Amy C Justice, Bradley E Aouizerat, Ke Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-03-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1012063&type=printable

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