Preparation and Evaluation of Mucus-Penetrating Inhalable Microparticles of Tiotropium Bromide Containing Sodium Glycocholate

Preparation and Evaluation of Mucus-Penetrating Inhalable Microparticles of Tiotropium Bromide Containing Sodium Glycocholate

This study aimed to prepare mucus-penetrating inhalable microparticles for dry powder inhalers and to evaluate their applicability in an asthma-induced rat model. Microparticles were prepared from water solutions containing tiotropium bromide, L-leucine, and sodium glycocholate (NaGc) as permeation...

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Bibliographic Details
Main Authors:	Yong-Bin Kwon, Ji-Hyun Kang, Young-Jin Kim, Dong-Wook Kim, Sung-Hoon Lee, Chun-Woong Park
Format:	Article
Language:	English
Published:	MDPI AG 2022-07-01
Series:	Pharmaceutics
Subjects:	tiotropium sodium glycocholate permeation enhancer aerodynamic properties Calu-3 cell asthma-induced rat model
Online Access:	https://www.mdpi.com/1999-4923/14/7/1409

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