Antimicrobial prescribing for children in China: data from point prevalence surveys in 18 tertiary centres in China in 2016–2017
Objectives The reports on evaluating the classification of antibiotic agents prescribed for Chinese children by combining WHO’s and China’s administrative categories were rare. This study aimed to investigate the pattern of antimicrobial agents prescribing for Chinese children in 2016.Settings 18 te...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2022-09-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/9/e059244.full |
| _version_ | 1828148569591250944 |
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| author | Xiang Ma Yonghong Yang Jiaosheng Zhang Wenshuang Zhang Lanfang Tang Daiyin Tian Keye Wu Yuejie Zheng Kunling Shen Jikui Deng |
| author_facet | Xiang Ma Yonghong Yang Jiaosheng Zhang Wenshuang Zhang Lanfang Tang Daiyin Tian Keye Wu Yuejie Zheng Kunling Shen Jikui Deng |
| author_sort | Xiang Ma |
| collection | DOAJ |
| description | Objectives The reports on evaluating the classification of antibiotic agents prescribed for Chinese children by combining WHO’s and China’s administrative categories were rare. This study aimed to investigate the pattern of antimicrobial agents prescribing for Chinese children in 2016.Settings 18 tertiary centres from nine provinces located in northern, southern, eastern and western China.Participants The antimicrobial prescribing data from the children admitted in medical wards, surgical wards and intensive care units were collected and analysed. A total of 3680 antibiotic prescriptions for Chinese children were included in the analysis.Primary and secondary outcome measures One-day point-prevalence surveys (PPSs) on antimicrobial prescribing were conducted among hospitalised children in China between 1 February 2016 and 28 February 2017. Five hospitals participated in the first PPS, 13 hospitals in the second PPS, 17 hospitals in the third PPS and 18 hospitals in the fourth PPS. Patterns of antibiotic use with a drug utilisation of 90%, Anatomical Therapeutical Chemical Classification, WHO Access, Watch and Reserve (AWaRe) (version 2019) and antibiotic classification in China were described retrospectively.Results A total of 4442 children and 3680 antibiotic prescriptions for Chinese children were included in the analysis. 2900 (65.3%) children received at least one ongoing antibiotic during the survey days. On the basis of WHO AWaRe classification, the proportion of antibiotics in the Watch group was 76.5% (2814/3680). According to the Management of Antibiotic Classification in China, 56.8% (2089/3680) and 16.1% (594/3680) of antibiotic prescriptions in the Restricted group and the Special group, respectively, were included into broad-spectrum antibiotics. The most common indication for antibiotics was bacterial lower respiratory tract infection (2044/3680, 55.5%).Conclusions The use of broad-spectrum antibiotics was frequent and excessive in hospitalised children in China in 2016. |
| first_indexed | 2024-04-11T21:16:58Z |
| format | Article |
| id | doaj.art-aa425a2e42564bb198ab76991383dd88 |
| institution | Directory Open Access Journal |
| issn | 2044-6055 |
| language | English |
| last_indexed | 2024-04-11T21:16:58Z |
| publishDate | 2022-09-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj.art-aa425a2e42564bb198ab76991383dd882022-12-22T04:02:47ZengBMJ Publishing GroupBMJ Open2044-60552022-09-0112910.1136/bmjopen-2021-059244Antimicrobial prescribing for children in China: data from point prevalence surveys in 18 tertiary centres in China in 2016–2017Xiang Ma0Yonghong Yang1Jiaosheng Zhang2Wenshuang Zhang3Lanfang Tang4Daiyin Tian5Keye Wu6Yuejie Zheng7Kunling Shen8Jikui Deng9Department of Respiratory, Children`s Hospital Affiliated to Shandong University & Jinan Children`s Hospital, Ji`nan, ChinaDepartment of Infectious Diseases, Shenzhen Children`s Hospital, Shenzhen, ChinaDepartment of Infectious Diseases, Shenzhen Children`s Hospital, Shenzhen, ChinaDepartment of Respiratory, Tianjin Children`s Hospital, Tianjin, ChinaDepartment of Respiratory, Children`s Hospital Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Respiratory Medicine, Children’s Hospital of Chongqing Medical University, Chongqing, Chongqing, ChinaDepartment of Cardiothoracic Surgery, Shenzhen Children`s Hospital, Shenzhen, ChinaDepartment of Respiratory, Shenzhen Children`s Hospital, Shenzhen, ChinaDepartment of Respiration, Beijing Children`s Hospital Affiliated to Capital Medical University, Beijing, ChinaDepartment of Infectious Diseases, Shenzhen Children`s Hospital, Shenzhen, ChinaObjectives The reports on evaluating the classification of antibiotic agents prescribed for Chinese children by combining WHO’s and China’s administrative categories were rare. This study aimed to investigate the pattern of antimicrobial agents prescribing for Chinese children in 2016.Settings 18 tertiary centres from nine provinces located in northern, southern, eastern and western China.Participants The antimicrobial prescribing data from the children admitted in medical wards, surgical wards and intensive care units were collected and analysed. A total of 3680 antibiotic prescriptions for Chinese children were included in the analysis.Primary and secondary outcome measures One-day point-prevalence surveys (PPSs) on antimicrobial prescribing were conducted among hospitalised children in China between 1 February 2016 and 28 February 2017. Five hospitals participated in the first PPS, 13 hospitals in the second PPS, 17 hospitals in the third PPS and 18 hospitals in the fourth PPS. Patterns of antibiotic use with a drug utilisation of 90%, Anatomical Therapeutical Chemical Classification, WHO Access, Watch and Reserve (AWaRe) (version 2019) and antibiotic classification in China were described retrospectively.Results A total of 4442 children and 3680 antibiotic prescriptions for Chinese children were included in the analysis. 2900 (65.3%) children received at least one ongoing antibiotic during the survey days. On the basis of WHO AWaRe classification, the proportion of antibiotics in the Watch group was 76.5% (2814/3680). According to the Management of Antibiotic Classification in China, 56.8% (2089/3680) and 16.1% (594/3680) of antibiotic prescriptions in the Restricted group and the Special group, respectively, were included into broad-spectrum antibiotics. The most common indication for antibiotics was bacterial lower respiratory tract infection (2044/3680, 55.5%).Conclusions The use of broad-spectrum antibiotics was frequent and excessive in hospitalised children in China in 2016.https://bmjopen.bmj.com/content/12/9/e059244.full |
| spellingShingle | Xiang Ma Yonghong Yang Jiaosheng Zhang Wenshuang Zhang Lanfang Tang Daiyin Tian Keye Wu Yuejie Zheng Kunling Shen Jikui Deng Antimicrobial prescribing for children in China: data from point prevalence surveys in 18 tertiary centres in China in 2016–2017 BMJ Open |
| title | Antimicrobial prescribing for children in China: data from point prevalence surveys in 18 tertiary centres in China in 2016–2017 |
| title_full | Antimicrobial prescribing for children in China: data from point prevalence surveys in 18 tertiary centres in China in 2016–2017 |
| title_fullStr | Antimicrobial prescribing for children in China: data from point prevalence surveys in 18 tertiary centres in China in 2016–2017 |
| title_full_unstemmed | Antimicrobial prescribing for children in China: data from point prevalence surveys in 18 tertiary centres in China in 2016–2017 |
| title_short | Antimicrobial prescribing for children in China: data from point prevalence surveys in 18 tertiary centres in China in 2016–2017 |
| title_sort | antimicrobial prescribing for children in china data from point prevalence surveys in 18 tertiary centres in china in 2016 2017 |
| url | https://bmjopen.bmj.com/content/12/9/e059244.full |
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