Current Advances in Checkpoint Inhibitors: Lessons from Non-Central Nervous System Cancers and Potential for Glioblastoma

The adaptive immune system depends on the sequence of antigen presentation, activation, and then inhibition to mount a proportionate response to a threat. Tumors evade the immune response partly by suppressing T-cell activity using immune checkpoints. The use of cytotoxic T-lymphocyte-associated pro...

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Bibliographic Details
Main Authors: Natasha Lakin, Robert Rulach, Stefan Nowicki, Kathreena M. Kurian
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00141/full