Application of alternative <i>de novo</i> motif recognition models for analysis of structural heterogeneity of transcription factor binding sites: a case study of FOXA2 binding sites

Application of alternative <i>de novo</i> motif recognition models for analysis of structural heterogeneity of transcription factor binding sites: a case study of FOXA2 binding sites

The most popular model for the search of ChIP-seq data for transcription factor binding sites (TFBS) is the positional weight matrix (PWM). However, this model does not take into account dependencies between nucleotide occurrences in different site positions. Currently, two recently proposed models,...

Full description

Bibliographic Details
Main Authors: A. V. Tsukanov, V. G. Levitsky, T. I. Merkulova
Format: Article
Language:English
Published: Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2021-03-01
Series:Вавиловский журнал генетики и селекции
Subjects:
transcription factor binding sites (tfbs)
tfbs <i>de novo</i> searching
chip-seq
heterogeneity of tfbs
Online Access:https://vavilov.elpub.ru/jour/article/view/2911

Similar Items

Similar Items