Chromatographic Scalable Method to Isolate Engineered Extracellular Vesicles Derived from Mesenchymal Stem Cells for the Treatment of Liver Fibrosis in Mice

Chromatographic Scalable Method to Isolate Engineered Extracellular Vesicles Derived from Mesenchymal Stem Cells for the Treatment of Liver Fibrosis in Mice

New therapeutic options for liver cirrhosis are needed. Mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) have emerged as a promising tool for delivering therapeutic factors in regenerative medicine. Our aim is to establish a new therapeutic tool that employs EVs derived from MSCs to...

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Bibliographic Details
Main Authors: Luciana M. Domínguez, Bárbara Bueloni, Ma. José Cantero, Milagros Albornoz, Natalia Pacienza, Celeste Biani, Carlos Luzzani, Santiago Miriuka, Mariana García, Catalina Atorrasagasti, Gustavo Yannarelli, Juan Bayo, Esteban Fiore, Guillermo Mazzolini
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
liver fibrosis
extracellular vesicles
mesenchymal stromal cells
chromatography EVs isolation
engineered EVs
Online Access:https://www.mdpi.com/1422-0067/24/11/9586

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