Multiplexed action-outcome representation by striatal striosome-matrix compartments detected with a mouse cost-benefit foraging task

The role that the striatum plays in tracking the association between actions and combinations of rewarding and aversive outcomes remains unclear. Here, by using both calcium imaging in mice and reinforcement learning models, the authors find that individual striatal neurons can encode associations b...

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Bibliografiske detaljer
Main Authors: Bernard Bloem, Rafiq Huda, Ken-ichi Amemori, Alex S. Abate, Gayathri Krishna, Anna L. Wilson, Cody W. Carter, Mriganka Sur, Ann M. Graybiel
Format: Article
Sprog:English
Udgivet: Nature Portfolio 2022-03-01
Serier:Nature Communications
Online adgang:https://doi.org/10.1038/s41467-022-28983-5