Pyrexia of Unknown Origin: A Perplexing Case
Pyrexia of Unknown Origin (PUO) is a common diagnostic dilemma in the medical wards. We present the case of a 64-year-old man who had presented with fever, fatigue, dry cough and bloody diarrhea. Over the next few days, he developed severe testicular pain and renal failure. Blood results revealed an...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2019-04-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/12785/40936_CE[Ra1]_F(SL)_PF1(AG_KM)_PN(SL).pdf |
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| author | Kiren George Koshy Moothezhathu Kesavadas Suresh Jithin John Karthik Vijayakumar Krishnakumar Madhavan |
| author_facet | Kiren George Koshy Moothezhathu Kesavadas Suresh Jithin John Karthik Vijayakumar Krishnakumar Madhavan |
| author_sort | Kiren George Koshy |
| collection | DOAJ |
| description | Pyrexia of Unknown Origin (PUO) is a common diagnostic dilemma in the medical wards. We present the case of a 64-year-old man who had presented with fever, fatigue, dry cough and bloody diarrhea. Over the next few days, he developed severe testicular pain and renal failure. Blood results revealed anaemia, raised ESR, negative ANA and negative ANCA. Renal biopsy showed crescentic glomerulonephritis. Repeat value of c-ANCA was positive which clinched the diagnosis of Granulomatosis with Polyangiitis (GPA). We present this case in order to illustrate the masquerading nature of the vasculitic syndromes and to emphasise the need to integrate clinical and laboratory clues to reach a diagnosis. |
| first_indexed | 2024-12-13T11:24:30Z |
| format | Article |
| id | doaj.art-aa4f8384fb59483d890c3b55af258bcf |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-13T11:24:30Z |
| publishDate | 2019-04-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-aa4f8384fb59483d890c3b55af258bcf2022-12-21T23:48:19ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2019-04-01134OD07OD0810.7860/JCDR/2019/40936.12785Pyrexia of Unknown Origin: A Perplexing CaseKiren George Koshy0Moothezhathu Kesavadas Suresh1Jithin John2Karthik Vijayakumar3Krishnakumar Madhavan4Junior Resident, Department of Internal Medicine, Government Medical College, Thiruvananthapuram, Trivandrum, Kerala, India.Professor, Department of Internal Medicine, Government Medical College, Thiruvananthapuram, Trivandrum, Kerala, India.Junior Resident, Department of Internal Medicine, Government Medical College, Thiruvananthapuram, Trivandrum, Kerala, India.Junior Resident, Department of Internal Medicine, Government Medical College, Thiruvananthapuram, Trivandrum, Kerala, India.Junior Resident, Department of Internal Medicine, Government Medical College, Thiruvananthapuram, Trivandrum, Kerala, India.Pyrexia of Unknown Origin (PUO) is a common diagnostic dilemma in the medical wards. We present the case of a 64-year-old man who had presented with fever, fatigue, dry cough and bloody diarrhea. Over the next few days, he developed severe testicular pain and renal failure. Blood results revealed anaemia, raised ESR, negative ANA and negative ANCA. Renal biopsy showed crescentic glomerulonephritis. Repeat value of c-ANCA was positive which clinched the diagnosis of Granulomatosis with Polyangiitis (GPA). We present this case in order to illustrate the masquerading nature of the vasculitic syndromes and to emphasise the need to integrate clinical and laboratory clues to reach a diagnosis.https://jcdr.net/articles/PDF/12785/40936_CE[Ra1]_F(SL)_PF1(AG_KM)_PN(SL).pdfcrescentic glomerulonephritispolyangiitisvasculitis |
| spellingShingle | Kiren George Koshy Moothezhathu Kesavadas Suresh Jithin John Karthik Vijayakumar Krishnakumar Madhavan Pyrexia of Unknown Origin: A Perplexing Case Journal of Clinical and Diagnostic Research crescentic glomerulonephritis polyangiitis vasculitis |
| title | Pyrexia of Unknown Origin: A Perplexing Case |
| title_full | Pyrexia of Unknown Origin: A Perplexing Case |
| title_fullStr | Pyrexia of Unknown Origin: A Perplexing Case |
| title_full_unstemmed | Pyrexia of Unknown Origin: A Perplexing Case |
| title_short | Pyrexia of Unknown Origin: A Perplexing Case |
| title_sort | pyrexia of unknown origin a perplexing case |
| topic | crescentic glomerulonephritis polyangiitis vasculitis |
| url | https://jcdr.net/articles/PDF/12785/40936_CE[Ra1]_F(SL)_PF1(AG_KM)_PN(SL).pdf |
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