Tumor Delivery of Ultrasound Contrast Agents Using Shiga Toxin B Subunit

Tumor Delivery of Ultrasound Contrast Agents Using Shiga Toxin B Subunit

The present study demonstrates the targeting of ultrasound contrast agents to human xenograft tumors by exploiting the overexpression of the glycolipid Gb3 in neovasculature. To this end, microbubbles were functionalized with a natural Gb3 ligand, the B subunit of the Shiga toxin (STxB). The targeti...

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Dades bibliogràfiques
Autors principals:	Olivier Couture, Estelle Dransart, Sabrina Dehay, Fariba Nemati, Didier Decaudin, Ludger Johannes, Mickael Tanter
Format:	Article
Idioma:	English
Publicat:	SAGE Publishing 2011-03-01
Col·lecció:	Molecular Imaging
Accés en línia:	https://doi.org/10.2310/7290.2010.00030

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