CLOSTRIDIUM DIFFICILE ASSOCIATED DIARRHEA IN MULTIDISCIPLINARY HOSPITAL

Currently, Clostridium difficile is the main reason of a nosocomial diarrhea, caused by uncontrolled antibacterial treatment. This problem is not paid, enough attention in our country. We analyzed. 536 cases of antibiotic associated infections using new immunochromotographical assay for express dete...

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Main Authors: N. F. Mulyar, S. A. Vereschagina, T. V. Fadeeva, G. P. Spasov, O. V. Kanya
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2012-09-01
Series:Acta Biomedica Scientifica
Subjects:
Online Access:https://www.actabiomedica.ru/jour/article/view/1093
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author N. F. Mulyar
S. A. Vereschagina
T. V. Fadeeva
G. P. Spasov
O. V. Kanya
author_facet N. F. Mulyar
S. A. Vereschagina
T. V. Fadeeva
G. P. Spasov
O. V. Kanya
author_sort N. F. Mulyar
collection DOAJ
description Currently, Clostridium difficile is the main reason of a nosocomial diarrhea, caused by uncontrolled antibacterial treatment. This problem is not paid, enough attention in our country. We analyzed. 536 cases of antibiotic associated infections using new immunochromotographical assay for express detection of Clostridium difficile. Since 2008 to 2011 evaluated rate of the positive tests was 28,7 % among the hospital patients. The first line therapy of this infection is vancomycine and metronidazole. We also observed increased incidence of mycosis, which accompanying the antibiotic associated diarrheas. During the same period the rate of Candida spp. infection was 50,8 % among the same patients. We used fluconazole and. amphotericine for the mycosis treatment. We also recommended to manage disbiosis during one year after discontinue of the treatment, and. we supposed reasonable to be managed by infectionist for this group of patients.
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spelling doaj.art-aa50b8ea913044dc9f4a01b65b9a20e62024-03-28T07:49:07ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962012-09-0105(1)72751039CLOSTRIDIUM DIFFICILE ASSOCIATED DIARRHEA IN MULTIDISCIPLINARY HOSPITALN. F. Mulyar0S. A. Vereschagina1T. V. Fadeeva2G. P. Spasov3O. V. Kanya4Irkutsk Regional clinical hospitalIrkutsk Regional clinical hospital; Irkutsk Regional Pathology DepartmentScientific Centre of Reconstructive and Restorative Surgery, Siberian Branch of RAMSIrkutsk Regional clinical hospitalIrkutsk Regional Pathology DepartmentCurrently, Clostridium difficile is the main reason of a nosocomial diarrhea, caused by uncontrolled antibacterial treatment. This problem is not paid, enough attention in our country. We analyzed. 536 cases of antibiotic associated infections using new immunochromotographical assay for express detection of Clostridium difficile. Since 2008 to 2011 evaluated rate of the positive tests was 28,7 % among the hospital patients. The first line therapy of this infection is vancomycine and metronidazole. We also observed increased incidence of mycosis, which accompanying the antibiotic associated diarrheas. During the same period the rate of Candida spp. infection was 50,8 % among the same patients. We used fluconazole and. amphotericine for the mycosis treatment. We also recommended to manage disbiosis during one year after discontinue of the treatment, and. we supposed reasonable to be managed by infectionist for this group of patients.https://www.actabiomedica.ru/jour/article/view/1093antibiotic associated diarrheaclostridium associated diarrheapseudomembranous colitisnosocomial infection
spellingShingle N. F. Mulyar
S. A. Vereschagina
T. V. Fadeeva
G. P. Spasov
O. V. Kanya
CLOSTRIDIUM DIFFICILE ASSOCIATED DIARRHEA IN MULTIDISCIPLINARY HOSPITAL
Acta Biomedica Scientifica
antibiotic associated diarrhea
clostridium associated diarrhea
pseudomembranous colitis
nosocomial infection
title CLOSTRIDIUM DIFFICILE ASSOCIATED DIARRHEA IN MULTIDISCIPLINARY HOSPITAL
title_full CLOSTRIDIUM DIFFICILE ASSOCIATED DIARRHEA IN MULTIDISCIPLINARY HOSPITAL
title_fullStr CLOSTRIDIUM DIFFICILE ASSOCIATED DIARRHEA IN MULTIDISCIPLINARY HOSPITAL
title_full_unstemmed CLOSTRIDIUM DIFFICILE ASSOCIATED DIARRHEA IN MULTIDISCIPLINARY HOSPITAL
title_short CLOSTRIDIUM DIFFICILE ASSOCIATED DIARRHEA IN MULTIDISCIPLINARY HOSPITAL
title_sort clostridium difficile associated diarrhea in multidisciplinary hospital
topic antibiotic associated diarrhea
clostridium associated diarrhea
pseudomembranous colitis
nosocomial infection
url https://www.actabiomedica.ru/jour/article/view/1093
work_keys_str_mv AT nfmulyar clostridiumdifficileassociateddiarrheainmultidisciplinaryhospital
AT savereschagina clostridiumdifficileassociateddiarrheainmultidisciplinaryhospital
AT tvfadeeva clostridiumdifficileassociateddiarrheainmultidisciplinaryhospital
AT gpspasov clostridiumdifficileassociateddiarrheainmultidisciplinaryhospital
AT ovkanya clostridiumdifficileassociateddiarrheainmultidisciplinaryhospital