Oleic Acid Exhibits Anti-Proliferative and Anti-Invasive Activities via the PTEN/AKT/mTOR Pathway in Endometrial Cancer

Oleic Acid Exhibits Anti-Proliferative and Anti-Invasive Activities via the PTEN/AKT/mTOR Pathway in Endometrial Cancer

Reprogramming of fatty acid metabolism promotes cell growth and metastasis through a variety of processes that stimulate signaling molecules, energy storage, and membrane biosynthesis in endometrial cancer. Oleic acid is one of the most important monounsaturated fatty acids in the human body, which...

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Bibliographic Details
Main Authors: Boer Deng, Weimin Kong, Hongyan Suo, Xiaochang Shen, Meredith A. Newton, Wesley C. Burkett, Ziyi Zhao, Catherine John, Wenchuan Sun, Xin Zhang, Yali Fan, Tianran Hao, Chunxiao Zhou, Victoria L. Bae-Jump
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cancers
Subjects:
endometrial cancer
oleic acid
cell proliferation
invasion
PTEN/AKT pathway
lipid droplets
Online Access:https://www.mdpi.com/2072-6694/15/22/5407

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