Intermittent Exposure to a 16 Hz Extremely Low Frequency Pulsed Electromagnetic Field Promotes Osteogenesis In Vitro through Activating Piezo 1-Induced Ca<sup>2+</sup> Influx in Osteoprogenitor Cells

Intermittent Exposure to a 16 Hz Extremely Low Frequency Pulsed Electromagnetic Field Promotes Osteogenesis In Vitro through Activating Piezo 1-Induced Ca<sup>2+</sup> Influx in Osteoprogenitor Cells

Exposure to extremely low frequency pulsed electromagnetic fields (ELF-PEMF) is supposed to simulate local EMF generated during mechanical stimulation of bone and may therefore be used to improve bone regeneration. This study aimed at optimizing the exposure strategy and investigating the underlying...

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Bibliographic Details
Main Authors: Yangmengfan Chen, Benedikt J. Braun, Maximilian M. Menger, Michael Ronniger, Karsten Falldorf, Tina Histing, Andreas K. Nussler, Sabrina Ehnert
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Journal of Functional Biomaterials
Subjects:
electromagnetic field
bone
piezo 1
calcium ions
osteoprogenitor cells
Online Access:https://www.mdpi.com/2079-4983/14/3/165

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