Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation

Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation

ESCRT-III complexes assemble in vivo inside membrane structures with a negative Gaussian curvature, but how membrane shape influences ESCRT-III polymerization remains unclear. Here authors use structural and biophysical methods to show how human ESCRT-III polymers assemble on positively curved membr...

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Bibliographic Details
Main Authors: Aurélie Bertin, Nicola de Franceschi, Eugenio de la Mora, Sourav Maity, Maryam Alqabandi, Nolwen Miguet, Aurélie di Cicco, Wouter H. Roos, Stéphanie Mangenot, Winfried Weissenhorn, Patricia Bassereau
Format: Article
Language:English
Published: Nature Portfolio 2020-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16368-5

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