Bullous leukemia cutis mimicking facial cellulitis
Abstract Bullous leukemia cutis is an uncommon clinical manifestation of cutaneous infiltration by leukemic cells, from B-cell chronic lymphocytic leukemia. We present the case of a 67-year-old, female, chronic lymphocytic leukemia patient. She was taking chlorambucil and developed facial edema with...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Dermatologia
2016-04-01
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| Series: | Anais Brasileiros de Dermatologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000200248&tlng=en |
| _version_ | 1819285131609767936 |
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| author | Luciana de Sales Caldato Juliana de Sousa Britto Ligia Niero-Melo Hélio Amante Miot |
| author_facet | Luciana de Sales Caldato Juliana de Sousa Britto Ligia Niero-Melo Hélio Amante Miot |
| author_sort | Luciana de Sales Caldato |
| collection | DOAJ |
| description | Abstract Bullous leukemia cutis is an uncommon clinical manifestation of cutaneous infiltration by leukemic cells, from B-cell chronic lymphocytic leukemia. We present the case of a 67-year-old, female, chronic lymphocytic leukemia patient. She was taking chlorambucil and developed facial edema with erythema and warmth, misjudged as facial cellulitis. Two days later, she developed bullous lesions in the arms, legs, neck and face. The histopathology of facial and bullous lesions confirmed leukemia cutis. All lesions disappeared following the administration of rituximab combined with cycles of fludarabine and cyclophosphamide. Although soft tissue infections are common complications in patients undergoing chemotherapy, leukemia cutis can also resemble cellulitis. |
| first_indexed | 2024-12-24T01:58:24Z |
| format | Article |
| id | doaj.art-aa5a64ea37514cf38cfd61ca23d4046d |
| institution | Directory Open Access Journal |
| issn | 0365-0596 |
| language | English |
| last_indexed | 2024-12-24T01:58:24Z |
| publishDate | 2016-04-01 |
| publisher | Sociedade Brasileira de Dermatologia |
| record_format | Article |
| series | Anais Brasileiros de Dermatologia |
| spelling | doaj.art-aa5a64ea37514cf38cfd61ca23d4046d2022-12-21T17:21:31ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962016-04-0191224824910.1590/abd1806-4841.20164557Bullous leukemia cutis mimicking facial cellulitisLuciana de Sales CaldatoJuliana de Sousa BrittoLigia Niero-MeloHélio Amante MiotAbstract Bullous leukemia cutis is an uncommon clinical manifestation of cutaneous infiltration by leukemic cells, from B-cell chronic lymphocytic leukemia. We present the case of a 67-year-old, female, chronic lymphocytic leukemia patient. She was taking chlorambucil and developed facial edema with erythema and warmth, misjudged as facial cellulitis. Two days later, she developed bullous lesions in the arms, legs, neck and face. The histopathology of facial and bullous lesions confirmed leukemia cutis. All lesions disappeared following the administration of rituximab combined with cycles of fludarabine and cyclophosphamide. Although soft tissue infections are common complications in patients undergoing chemotherapy, leukemia cutis can also resemble cellulitis.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000200248&tlng=enDermatologyLeukemiaSkin diseases, vesiculobullous |
| spellingShingle | Luciana de Sales Caldato Juliana de Sousa Britto Ligia Niero-Melo Hélio Amante Miot Bullous leukemia cutis mimicking facial cellulitis Anais Brasileiros de Dermatologia Dermatology Leukemia Skin diseases, vesiculobullous |
| title | Bullous leukemia cutis mimicking facial cellulitis |
| title_full | Bullous leukemia cutis mimicking facial cellulitis |
| title_fullStr | Bullous leukemia cutis mimicking facial cellulitis |
| title_full_unstemmed | Bullous leukemia cutis mimicking facial cellulitis |
| title_short | Bullous leukemia cutis mimicking facial cellulitis |
| title_sort | bullous leukemia cutis mimicking facial cellulitis |
| topic | Dermatology Leukemia Skin diseases, vesiculobullous |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000200248&tlng=en |
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