Association analysis of maternal MTHFR gene polymorphisms and the occurrence of congenital heart disease in offspring

Association analysis of maternal MTHFR gene polymorphisms and the occurrence of congenital heart disease in offspring

Abstract Background Although many studies showed that the risk of congenital heart disease (CHD) was closely related to genetic factors, the exact pathogenesis is still unknown. Our study aimed to comprehensively assess the association of single nucleotide polymorphisms (SNPs) of maternal MTHFR gene...

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Bibliographic Details
Main Authors: Mengting Sun, Tingting Wang, Peng Huang, Jingyi Diao, Senmao Zhang, Jinqi Li, Liu Luo, Yihuan Li, Letao Chen, Yiping Liu, Jianhui Wei, Xinli Song, Xiaoqi Sheng, Jiabi Qin
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Cardiovascular Disorders
Subjects:
Congenital heart disease
Folate metabolism
MTHFR
Polymorphisms
Interaction
Online Access:https://doi.org/10.1186/s12872-021-02117-z

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