Determinants of Diabetic Complications: A Population-Based Case-Control Study
Background and Objectives: Diabetes is considered as one of the most common endocrine disorders worldwide. The aim of this study was to investigate the factors associated with diabetic complications. Methods: A case-control study was performed on the data of 70089 diabetic patients (4622 cases and...
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| Format: | Article |
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Tehran University of Medical Sciences
2020-11-01
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| Series: | مجله اپیدمیولوژی ایران |
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| Online Access: | http://irje.tums.ac.ir/article-1-6660-en.html |
| _version_ | 1818692766140465152 |
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| author | HR Bahrami Taghanaki E Mosa Farkhani R Eftekhari Gol P Bahrami Taghanaki S Bokaei A Taghipour B Beygi |
| author_facet | HR Bahrami Taghanaki E Mosa Farkhani R Eftekhari Gol P Bahrami Taghanaki S Bokaei A Taghipour B Beygi |
| author_sort | HR Bahrami Taghanaki |
| collection | DOAJ |
| description | Background and Objectives: Diabetes is considered as one of the most common endocrine disorders worldwide. The aim of this study was to investigate the factors associated with diabetic complications.
Methods: A case-control study was performed on the data of 70089 diabetic patients (4622 cases and 53613 controls) extracted from the SINA Electronic Health Record (SinaEHR®) in a population covered by Mashhad University of Medical Sciences in 2018. The effect of independent variables on the likelihood of diabetic complications was investigated using single-variable and multivariate logistic regression models with the control of the potential confounding effects.
Results: Using the multivariate logistic regression, the odds of developing diabetic complications were 0.35 (0.31-0.38) for living in the city, 0.73(0.67-0.79) for living in the suburbs and 0.31(0.28-0.33) for living in rural areas relative to the metropolises, 0.84 (0.78-0.91) for illiterate subjects, 0.70 (0.66-0.75) for physical activity, 1.51(1.34-1.71) for stage 1 hypertension and 1.87 (1.43-2.44) for stage 2 hypertension relative to normal blood pressure, 0.79(0.74-0.85) for uncontrolled low density lipoprotein and 1.42(1.33-1.51) for uncontrolled hemoglobin A1C.
Conclusion: Various risk factors were identified to increase the odds ratio of diabetic complications. The most important risk factors were uncontrolled glycosylated hemoglobin and stage 1 and 2 hypertension. Control of these factors can reduce the chance of diabetic complications in diabetic patients. |
| first_indexed | 2024-12-17T13:03:00Z |
| format | Article |
| id | doaj.art-aa60f190691f488abfe2202917ce959e |
| institution | Directory Open Access Journal |
| issn | 1735-7489 2228-7507 |
| language | fas |
| last_indexed | 2024-12-17T13:03:00Z |
| publishDate | 2020-11-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | مجله اپیدمیولوژی ایران |
| spelling | doaj.art-aa60f190691f488abfe2202917ce959e2022-12-21T21:47:19ZfasTehran University of Medical Sciencesمجله اپیدمیولوژی ایران1735-74892228-75072020-11-01163220229Determinants of Diabetic Complications: A Population-Based Case-Control StudyHR Bahrami Taghanaki0E Mosa Farkhani1R Eftekhari Gol2P Bahrami Taghanaki3S Bokaei4A Taghipour5B Beygi6 Associate Professor of Complementary and Chinese Medicine, Persian and Complementary Medicine Faculty, Mashhad University of Medical Sciences, Mashhad, Iran PhD in Epidemiology, Mashhad University of Medical Sciences, Mashhad, Iran Department of Health Network Development and Health Promotion, Khorasan Razavi Province Health Center, Mashhad, Iran Medical student, Faculty of medicine, Mashhad university of Medical Science, Mashhad, Iran Department of Food Hygiene and Epidemiology, Faculty of Veterinary medicine, University of Tehran, Tehran, Iran; Uro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran MD, PhD in Epidemiology, Associate Professor, Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Environmental Health Engineering, Environmental Health Engineering, East Educational Research division of Drug abuse and addictive behavior, Psychiatry and Behavioral Sciences Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Background and Objectives: Diabetes is considered as one of the most common endocrine disorders worldwide. The aim of this study was to investigate the factors associated with diabetic complications. Methods: A case-control study was performed on the data of 70089 diabetic patients (4622 cases and 53613 controls) extracted from the SINA Electronic Health Record (SinaEHR®) in a population covered by Mashhad University of Medical Sciences in 2018. The effect of independent variables on the likelihood of diabetic complications was investigated using single-variable and multivariate logistic regression models with the control of the potential confounding effects. Results: Using the multivariate logistic regression, the odds of developing diabetic complications were 0.35 (0.31-0.38) for living in the city, 0.73(0.67-0.79) for living in the suburbs and 0.31(0.28-0.33) for living in rural areas relative to the metropolises, 0.84 (0.78-0.91) for illiterate subjects, 0.70 (0.66-0.75) for physical activity, 1.51(1.34-1.71) for stage 1 hypertension and 1.87 (1.43-2.44) for stage 2 hypertension relative to normal blood pressure, 0.79(0.74-0.85) for uncontrolled low density lipoprotein and 1.42(1.33-1.51) for uncontrolled hemoglobin A1C. Conclusion: Various risk factors were identified to increase the odds ratio of diabetic complications. The most important risk factors were uncontrolled glycosylated hemoglobin and stage 1 and 2 hypertension. Control of these factors can reduce the chance of diabetic complications in diabetic patients.http://irje.tums.ac.ir/article-1-6660-en.htmlcomplications of diabetesrisk factorscase-control studylogistic regression |
| spellingShingle | HR Bahrami Taghanaki E Mosa Farkhani R Eftekhari Gol P Bahrami Taghanaki S Bokaei A Taghipour B Beygi Determinants of Diabetic Complications: A Population-Based Case-Control Study مجله اپیدمیولوژی ایران complications of diabetes risk factors case-control study logistic regression |
| title | Determinants of Diabetic Complications: A Population-Based Case-Control Study |
| title_full | Determinants of Diabetic Complications: A Population-Based Case-Control Study |
| title_fullStr | Determinants of Diabetic Complications: A Population-Based Case-Control Study |
| title_full_unstemmed | Determinants of Diabetic Complications: A Population-Based Case-Control Study |
| title_short | Determinants of Diabetic Complications: A Population-Based Case-Control Study |
| title_sort | determinants of diabetic complications a population based case control study |
| topic | complications of diabetes risk factors case-control study logistic regression |
| url | http://irje.tums.ac.ir/article-1-6660-en.html |
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