The Role of Bradykinin Receptors in Hereditary Angioedema Due to C1-Inhibitor Deficiency

The Role of Bradykinin Receptors in Hereditary Angioedema Due to C1-Inhibitor Deficiency

Background: Hereditary angioedema (HAE) is a rare, genetic disease caused by the decreased level or function of the C1 inhibitor. The primary mediator of symptoms in HAE is bradykinin acting through its two receptors, namely receptors 1 (BR1) and 2 (BR2). Although BR2 is well characterized, the role...

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Bibliographic Details
Main Authors: Wojciech Dyga, Aleksander Obtulowicz, Tomasz Mikolajczyk, Anna Bogdali, Pawel Dubiela, Krystyna Obtulowicz
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
angioedema
bradykinin
bradykinin receptors
C1 inhibitor
HAE
Online Access:https://www.mdpi.com/1422-0067/23/18/10332

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